COVID-19 and the vasculature: current aspects and long-term consequences
B Martinez-Salazar, M Holwerda, C Stuedle… - Frontiers in cell and …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was first identified in
December 2019 as a novel respiratory pathogen and is the causative agent of Corona Virus …
December 2019 as a novel respiratory pathogen and is the causative agent of Corona Virus …
Cell-specific mechanisms in the heart of COVID-19 patients
From the onset of the pandemic, evidence of cardiac involvement in acute COVID-19
abounded. Cardiac presentations ranged from arrhythmias to ischemia, myopericarditis …
abounded. Cardiac presentations ranged from arrhythmias to ischemia, myopericarditis …
MAVS signaling is required for preventing persistent chikungunya heart infection and chronic vascular tissue inflammation
Chikungunya virus (CHIKV) infection has been associated with severe cardiac
manifestations, yet, how CHIKV infection leads to heart disease remains unknown. Here, we …
manifestations, yet, how CHIKV infection leads to heart disease remains unknown. Here, we …
Long-term effect of SARS-CoV-2 infection on cardiovascular outcomes and all-cause mortality
A Aleksova, AL Fluca, G Gagno, A Pierri, L Padoan… - Life sciences, 2022 - Elsevier
Since the very beginning of the coronavirus disease 2019 (COVID-19) pandemic in early
2020, it was evident that patients with cardiovascular disease (CVD) were at an increased …
2020, it was evident that patients with cardiovascular disease (CVD) were at an increased …
Using autopsies to dissect COVID-19 pathogenesis
The emergence of SARS-CoV-2 has resulted in millions of deaths as a result of COVID-19.
Suitable models were missing at the beginning of the pandemic, and studies investigating …
Suitable models were missing at the beginning of the pandemic, and studies investigating …
Spatiotemporal transcriptomics reveals pathogenesis of viral myocarditis
A significant fraction of sudden death in children and young adults is due to viral myocarditis,
an inflammatory disease of the heart. In this study, by using integrated single-cell and spatial …
an inflammatory disease of the heart. In this study, by using integrated single-cell and spatial …
How does COVID-19 affect the heart?
Abstract Purpose of Review Cardiac consequences occur in both acute COVID-19 and post-
acute sequelae of COVID-19 (PASC). Here, we highlight the current understanding about …
acute sequelae of COVID-19 (PASC). Here, we highlight the current understanding about …
SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis
SARS-CoV-2 infection causes COVID-19, a severe acute respiratory disease associated
with cardiovascular complications including long-term outcomes. The presence of virus in …
with cardiovascular complications including long-term outcomes. The presence of virus in …
Human cardiac organoids to model COVID‐19 cytokine storm induced cardiac injuries
DC Arhontoulis, CM Kerr, D Richards… - Journal of Tissue …, 2022 - Wiley Online Library
Acute cardiac injuries occur in 20%–25% of hospitalized COVID‐19 patients. Herein, we
demonstrate that human cardiac organoids (hCOs) are a viable platform to model the …
demonstrate that human cardiac organoids (hCOs) are a viable platform to model the …
The tissue-specific transcriptional landscape underlines the involvement of endothelial cells in health and disease
S Parab, E Setten, E Astanina, F Bussolino… - Pharmacology & …, 2023 - Elsevier
Endothelial cells (ECs) that line vascular and lymphatic vessels are being increasingly
recognized as important to organ function in health and disease. ECs participate not only in …
recognized as important to organ function in health and disease. ECs participate not only in …