Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …

Fungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated
with high morbidity and mortality (> 70%), and presents numerous challenges during clinical …

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

Invasive infection caused by Candida species is a condition associated with medical
progress. It is a common health care–associated infection (HAI), and is widely recognized as …

Extracellular matrixes (ECMs), such as the cell walls and biofilms, are important for
supporting cell integrity and function and regulating intercellular communication. These …

Bloodstream infection (BSI) is defined by positive blood cultures in a patient with systemic
signs of infection and may be either secondary to a documented source or primary—that is …

Candida species, belonging to commensal microbial communities in humans, cause
opportunistic infections in individuals with impaired immunity. Pathogens encountered in …

Candida albicans is among the most prevalent fungal species of the human microbiota and
asymptomatically colonizes healthy individuals. However, it is also an opportunistic …

Invasive fungal infections continue to appear in record numbers as the
immunocompromised population of the world increases, owing partially to the increased …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …