Three decades of ultrasound contrast agents: a review of the past, present and future improvements

P Frinking, T Segers, Y Luan, F Tranquart - Ultrasound in medicine & …, 2020 - Elsevier
Initial reports from the 1960s describing the observations of ultrasound contrast
enhancement by tiny gaseous bubbles during echocardiographic examinations prompted …

[HTML][HTML] Micro/nano-bubble-assisted ultrasound to enhance the EPR effect and potential theranostic applications

L Duan, L Yang, J Jin, F Yang, D Liu, K Hu, Q Wang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Drug delivery for tumor theranostics involves the extensive use of the enhanced permeability
and retention (EPR) effect. Previously, various types of nanomedicines have been …

Surfactant dynamics: hidden variables controlling fluid flows

H Manikantan, TM Squires - Journal of fluid mechanics, 2020 - cambridge.org
Surfactants–molecules and particles that preferentially adsorb to fluid interfaces–play a
ubiquitous role in the fluids of industry, of nature and of life. Since most surfactants cannot be …

[HTML][HTML] Ultrasound contrast agent modeling: a review

M Versluis, E Stride, G Lajoinie, B Dollet… - Ultrasound in medicine & …, 2020 - Elsevier
Ultrasound is extensively used in medical imaging, being safe and inexpensive and
operating in real time. Its scope of applications has been widely broadened by the use of …

The role of ultrasound-driven microbubble dynamics in drug delivery: from microbubble fundamentals to clinical translation

S Roovers, T Segers, G Lajoinie, J Deprez, M Versluis… - Langmuir, 2019 - ACS Publications
In the last couple of decades, ultrasound-driven microbubbles have proven excellent
candidates for local drug delivery applications. Besides being useful drug carriers …

Towards controlled drug delivery in brain tumors with microbubble-enhanced focused ultrasound

S Schoen Jr, MS Kilinc, H Lee, Y Guo… - Advanced drug delivery …, 2022 - Elsevier
Brain tumors are particularly challenging malignancies, due to their location in a structurally
and functionally distinct part of the human body–the central nervous system (CNS). The CNS …

Acoustic behavior of microbubbles and implications for drug delivery

K Kooiman, HJ Vos, M Versluis, N De Jong - Advanced drug delivery …, 2014 - Elsevier
Ultrasound contrast agents are valuable in diagnostic ultrasound imaging, and they
increasingly show potential for drug delivery. This review focuses on the acoustic behavior …

Bubble dynamics in soft and biological matter

B Dollet, P Marmottant, V Garbin - Annual Review of Fluid …, 2019 - annualreviews.org
Bubbles are present in a large variety of emerging applications, from advanced materials to
biology and medicine, as either laser-generated or acoustically driven bubbles. In these …

Ultrasound, cavitation bubbles and their interaction with cells

J Wu, WL Nyborg - Advanced drug delivery reviews, 2008 - Elsevier
This article reviews the basic physics of ultrasound generation, acoustic field, and both
inertial and non-inertial acoustic cavitation in the context of localized gene and drug delivery …

Applications of acoustics and cavitation to noninvasive therapy and drug delivery

CC Coussios, RA Roy - Annu. Rev. Fluid Mech., 2008 - annualreviews.org
Biomedical acoustics is rapidly evolving from a diagnostic modality into a therapeutic tool,
and acoustic cavitation is often the common denominator in a wide range of new therapeutic …