Proanthocyanidins (PA) are polyphenol compounds that are widely distributed in the bark,
fruit core, skin, or seeds of various plants. Anthocyanidins are water‐soluble natural …

Seeds contain a variety of phytochemicals that exhibit a wide range of biological activities.
Plant-derived compounds are often investigated for their antioxidant, anti-inflammatory …

We evaluated the potential of apple to reduce inflammation. Phenolic compounds and
triterpenes were analyzed in 109 apple cultivars. Total phenolics ranged from 29 to 7882 μg …

Procyanidin is an abundant polyphenol found in nature. It is composed of flavan-3-ol units,
including catechin and epicatechin. Procyanidin is a polyphenolic polymer found in …

Chronic inflammation is a hallmark of several pathologies, such as rheumatoid arthritis,
gastritis, inflammatory bowel disease, atherosclerosis and cancer. A wide range of anti …

The inflammatory response has been implicated in the pathogenesis of many chronic
diseases. Thus, the modulation of the inflammatory response by the consumption of …

Toll-like receptor 4 (TLR4), along with its accessory protein myeloid differentiation factor 2
(MD-2), builds a heterodimeric complex that specifically recognizes lipopolysaccharides …

The pathogenesis of inflammatory bowel disease (IBD), including Crohn's disease, is a
subject of increasing interest. Loss-of-function mutations in nucleotide‑binding …

Proanthocyanidins, widespread in natural plant sources, are bioactive substances that
exhibit broad benefits to human health. Of note, proanthocyanidins have been reported to …

Mi (cro) RNAs are small non-coding RNAs of 18-25 nucleotides in length that modulate
gene expression at the post-transcriptional level. These RNAs have been shown to be …