The diagnosis and management of Cushing's syndrome in pregnancy

R Hamblin, A Coulden, A Fountas… - Journal of …, 2022 - Wiley Online Library
Endogenous Cushing's syndrome (CS) is rarely encountered during pregnancy. Clinical and
biochemical changes in healthy pregnancy overlap with those seen in pregnancy …

[HTML][HTML] Cushing's disease: adrenal steroidogenesis inhibitors

R Pivonello, C Simeoli, N Di Paola, A Colao - Pituitary, 2022 - Springer
Abstract Cushing's disease (CD), caused by an adrenocorticotropic hormone (ACTH)-
secreting pituitary tumor, is the most common form of Cushing's syndrome (CS), accounting …

Sex differences in offspring risk and resilience following 11β-hydroxylase antagonism in a rodent model of maternal immune activation

J Martz, MA Shelton, L Geist, ML Seney… - …, 2024 - nature.com
Maternal immune activation (MIA) puts offspring at greater risk for neurodevelopmental
disorders associated with impaired social behavior. While it is known that immune signaling …

Approach to the patient treated with steroidogenesis inhibitors

F Castinetti, LK Nieman, M Reincke… - The Journal of …, 2021 - academic.oup.com
Steroidogenesis inhibitors can be given to control the hypercortisolism of Cushing's
syndrome in various situations: when surgery has been unsuccessful or not possible; in …

Updates in adrenal steroidogenesis inhibitors for Cushing's syndrome–a practical guide

EV Varlamov, AJ Han, M Fleseriu - Best Practice & Research Clinical …, 2021 - Elsevier
Medical therapy is essential in the management of patients with Cushing's syndrome (CS)
when curative surgery has failed, surgery is not feasible, when awaiting radiation effect, and …

Conundrums of Diagnosis and Management of Cushing's Syndrome in Pregnancy

ML Gheorghiu, M Fleseriu - Endocrinology and Metabolism …, 2024 - endo.theclinics.com
Endogenous Cushing's syndrome (CS) is a rare disease, with an estimated global, general
population incidence of approximately 2 to 4.5 per million per year. 1, 2 Although most …

An evaluation of pharmacological options for Cushing's disease: what are the state-of-the-art options?

M Martino, N Aboud, B Lucchetti, G Salvio… - Expert Opinion on …, 2023 - Taylor & Francis
ABSTRACT Introduction Untreated Cushing's syndrome (CS) is associated with significant
morbidity and mortality. Cortisol normalization is a key goal to treatment. Pituitary surgery …

库欣综合征的诊疗进展

刘岑, 赵紫楠, 陈頔, 胡欣 - 罕见病研究, 2024 - jrd.chard.org.cn
库欣综合征(CS) 是一种由肾上腺皮质分泌过多糖皮质激素引起的内分泌疾病,
其诊断与治疗均具挑战性. 诊断过程需结合实验室和影像学检查, 进行筛查, 定性及定位 …

Endocrine hypertension in pregnancy

F Jebasingh, N Thomas - Endocrine Hypertension, 2023 - Elsevier
Pregnancy is a state wherein there are several physiological hormonal changes. Moreover,
hypertension is common during pregnancy. A number of hormonal alterations could induce …

[HTML][HTML] Cushing disease treated successfully with metyrapone during pregnancy

IR Bass, A Leiter, Y Pozharny, R Shrivastava… - AACE Clinical Case …, 2022 - Elsevier
Background Cushing disease (CD) during pregnancy is a rare but serious disease that
adversely impacts maternal and fetal outcomes. As the sole use of metyrapone in the …