Anesthetic agents of plant origin: a review of phytochemicals with anesthetic activity

H Tsuchiya - Molecules, 2017 - mdpi.com
The majority of currently used anesthetic agents are derived from or associated with natural
products, especially plants, as evidenced by cocaine that was isolated from coca …

A review on garcinia kola heckel: traditional uses, phytochemistry, pharmacological activities, and toxicology

O Emmanuel, ME Uche, ED Dike, LR Etumnu… - Biomarkers, 2022 - Taylor & Francis
Purpose Garcinia kola is a medicinal plant commonly known as bitter kola. It is utilised in
ethnomedicine for the treatment of diarrhoea, bronchitis, bacterial infection, cough, hepatitis …

Harmful and protective effects of phenolic compounds from African medicinal plants

AT Mbaveng, Q Zhao, V Kuete - Toxicological survey of African medicinal …, 2014 - Elsevier
Phenolic phytochemicals include flavonoids, phenolic acids, tannins, lignans, coumarins,
quinones, xanthones, cucurmin, and several other plant compounds owing hydroxyl group …

Neuroprotective effects of dietary plants and phytochemicals against radiation-induced cognitive and behavioral deficits: A comprehensive review of evidence and …

SV Raghu, AK Kudva, RG Krishnamurthy, J Mudgal… - Food & function, 2023 - pubs.rsc.org
Exposure to ionizing radiation (IR) is a common occurrence in clinical practice and incidents
involving nuclear detonation or nuclear reactor accidents. IR triggers cellular events that …

[HTML][HTML] Kolaviron abates busulfan-induced episodic memory deficit and testicular dysfunction in rats: the implications for neuroendopathobiological changes during …

MO Oyovwi, B Ben-Azu, TP Edesiri, E Victor… - Biomedicine & …, 2021 - Elsevier
Busulfan is a popular antileukemia chemotherapeutic alkylating agent widely known to
induce variety of serious adverse effects including chemobrain-related cognitive …

Novel iodoquinazolinones bearing sulfonamide moiety as potential antioxidants and neuroprotectors

AM Soliman, WM Ghorab, DM Lotfy, HM Karam… - Scientific Reports, 2023 - nature.com
In a search for new antioxidants, a set of new iodoquinazolinone derivatives bearing
benzenesulfonamide moiety and variable acetamide pharmacophores 5–17 were designed …

Kolaviron, a flavonoid‐rich extract ameliorates busulfan‐induced chemo‐brain and testicular damage in male rats through inhibition of oxidative stress, inflammatory …

EP Tesi, B Ben‐Azu, OO Mega, J Mordi… - Journal of food …, 2022 - Wiley Online Library
Previous reports revealed that increased oxidative stress with up‐regulated inflammatory
proteins and apoptotic factors have serious implications in busulfan‐induced chemo‐brain …

[HTML][HTML] Type-2 diabetic rat heart: The effect of kolaviron on mTOR-1, P70S60K, PKC-α, NF-kB, SOD-2, NRF-2, eNOS, AKT-1, ACE, and P38 MAPK gene expression …

JO Adoga, ML Channa, A Nadar - Biomedicine & Pharmacotherapy, 2022 - Elsevier
It has been established that genetic factors partially contribute to type-2 diabetes and
vascular disease development. This study determined the effect of kolaviron on the …

Ameliorative effect of kolaviron, a biflavonoid complex from Garcinia kola seeds against scopolamine-induced memory impairment in rats: role of antioxidant defense …

IO Ishola, FM Adamson, OO Adeyemi - Metabolic brain disease, 2017 - Springer
In Alzheimer's disease (AD) basal forebrain cholinergic neurons appear to be targeted
primarily in early stages of the disease. Scopolamine (muscarinic receptor antagonist) has …

Fruits and their phytochemicals in mitigating the ill effects of ionizing radiation: review on the existing scientific evidence and way forward

SV Raghu, S Rao, V Kini, AK Kudva, T George… - Food & Function, 2023 - pubs.rsc.org
Although helpful in treating cancer, exposure to ionizing radiation can sometimes cause
severe side effects, negating its benefit. In addition to its use in clinics, a nontoxic …