The enigmatic world of fungal melanin: a comprehensive review

M Suthar, L Dufossé, SK Singh - Journal of Fungi, 2023 - mdpi.com
Synthetic dyes are generally not safe for human health or the environment, leading to the
continuous search and growing demand for natural pigments that are considered safer …

Unraveling synthesis of the cryptococcal cell wall and capsule

ZA Wang, LX Li, TL Doering - Glycobiology, 2018 - academic.oup.com
Fungal pathogens cause devastating infections in millions of individuals each year,
representing a huge but underappreciated burden on human health. One of these, the …

The protective role and mechanism of melanin for Aspergillus niger and Aspergillus flavus against chlorine-based disinfectants

X Xu, R Cao, K Li, Q Wan, G Wu, Y Lin, T Huang… - Water Research, 2022 - Elsevier
Melanin is a critical component of fungal cell wall which protect fungi from adverse
environmental tress. However, the role of melanin for fungi during the disinfection with …

Peeling the onion: the outer layers of Cryptococcus neoformans

DP Agustinho, LC Miller, LX Li… - Memórias do Instituto …, 2018 - SciELO Brasil
Cryptococcus neoformans is an opportunistic fungal pathogen that is ubiquitous in the
environment. It causes a deadly meningitis that is responsible for over 180,000 deaths …

Maintenance of mitochondrial morphology in Cryptococcus neoformans is critical for stress resistance and virulence

AL Chang, TL Doering - MBio, 2018 - Am Soc Microbiol
Mitochondria are essential organelles that act in pathways including ATP production, β-
oxidation, and clearance of reactive oxygen species. They occur as a complex reticular …

The aggregation of Aspergillus spores and the impact on their inactivation by chlorine-based disinfectants

H Zhang, X Xu, L Tan, Z Liang, R Cao, Q Wan, H Xu… - Water Research, 2021 - Elsevier
The formation of fungal biofilm goes through some different states, including monodisperse
state, aggregated state, germinated state, hyphal and biofilm. The aggregation of spores is a …

The transcription factor Pdr802 regulates titan cell formation and pathogenicity of Cryptococcus neoformans

JCV Reuwsaat, DP Agustinho, H Motta, AL Chang… - Mbio, 2021 - Am Soc Microbiol
Cryptococcus neoformans is a ubiquitous, opportunistic fungal pathogen that kills almost
200,000 people worldwide each year. It is acquired when mammalian hosts inhale the …

Inhibiting DHN- and DOPA-melanin biosynthesis pathway increased the therapeutic value of itraconazole in Madurella mycetomatis infected Galleria mellonella

W Lim, M Konings, F Parel, K Eadie, N Strepis… - Medical …, 2022 - academic.oup.com
Eumycetoma is a neglected tropical disease, and Madurella mycetomatis, the most common
causative agent of this disease forms black grains in hosts. Melanin was discovered to be …

A Plumieridine-Rich Fraction From Allamanda polyantha Inhibits Chitinolytic Activity and Exhibits Antifungal Properties Against Cryptococcus neoformans

E Silva e Souza, VA Barcellos, N Sbaraini… - Frontiers in …, 2020 - frontiersin.org
Cryptococcosis is a fungal infection caused mainly by the pathogenic yeasts Cryptococcus
neoformans and Cryptococcus gattii. The infection initiates with the inhalation of propagules …

The emerging pathogens: Nature, status, and threat

ME Kambouris, Y Manoussopoulos… - … and Applications of …, 2021 - books.google.com
The fast development of resistance and the ability to disseminate it within a single
generation through mobile DNA elements (Stokes and Gillings, 2011) is a factor that …