Toxicology and pharmacology of synthetic organoselenium compounds: An update
Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …
compounds and some naturally occurring organoselenium amino acids. The use of …
The role of selenium in arsenic and cadmium toxicity: an updated review of scientific literature
I Zwolak - Biological trace element research, 2020 - Springer
Abstract Arsenic (As) and cadmium (Cd) are elements arousing major public health
concerns associated with environmental pollution, high toxicity potential, and carcinogenic …
concerns associated with environmental pollution, high toxicity potential, and carcinogenic …
Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury
Essential metals are crucial for the maintenance of cell homeostasis. Among the 23
elements that have known physiological functions in humans, 12 are metals, including iron …
elements that have known physiological functions in humans, 12 are metals, including iron …
Mechanisms of methylmercury-induced neurotoxicity: evidence from experimental studies
Neurological disorders are common, costly, and can cause enduring disability. Although
mostly unknown, a few environmental toxicants are recognized causes of neurological …
mostly unknown, a few environmental toxicants are recognized causes of neurological …
Rethinking mercury: the role of selenium in the pathophysiology of mercury toxicity
HA Spiller - Clinical toxicology, 2018 - Taylor & Francis
Introduction: There is increasing evidence that the pathophysiological target of mercury is in
fact selenium, rather than the covalent binding of mercury to sulfur in the body's ubiquitous …
fact selenium, rather than the covalent binding of mercury to sulfur in the body's ubiquitous …
Rutin ameliorates mercuric chloride-induced hepatotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis
Objective Mercury is a global environmental pollutant and is responsible for several organ
pathophysiology including oxidative stress-induced liver disorders. Therefore, the present …
pathophysiology including oxidative stress-induced liver disorders. Therefore, the present …
The role of metallobiology and amyloid‐β peptides in Alzheimer's disease
J. Neurochem.(2012) 120 (Suppl. 1), 149–166. Abstract The biggest risk factor for
Alzheimer's disease is the process of ageing, but the mechanisms that lead to the …
Alzheimer's disease is the process of ageing, but the mechanisms that lead to the …
Oxidative stress in MeHg-induced neurotoxicity
Methylmercury (MeHg) is an environmental toxicant that leads to long-lasting neurological
and developmental deficits in animals and humans. Although the molecular mechanisms …
and developmental deficits in animals and humans. Although the molecular mechanisms …
Glutathione antioxidant system and methylmercury-induced neurotoxicity: An intriguing interplay
Methylmercury (MeHg) is a toxic chemical compound naturally produced mainly in the
aquatic environment through the methylation of inorganic mercury catalyzed by aquatic …
aquatic environment through the methylation of inorganic mercury catalyzed by aquatic …
Organoselenium compounds as mimics of selenoproteins and thiol modifier agents
Selenium is an essential trace element for animals and its role in the chemistry of life relies
on a unique functional group: the selenol (–SeH) group. The selenol group participates in …
on a unique functional group: the selenol (–SeH) group. The selenol group participates in …