DNA sequencing has identified recurrent mutations that drive the aggressiveness of prostate
cancers. Surprisingly, the influence of genomic, epigenomic, and transcriptomic …

BACKGROUND Members of the cysteine-rich secretory proteins (CRISPS), antigen 5 (Ag5)
and pathogenesis-related 1 (Pr-1)(CAP) superfamily of proteins are found across the …

The idea that amyloid fibrils and other types of protein aggregates are toxic for cells has
been challenged by the discovery of a variety of functional aggregates. However, an …

Background TMPRSS2-ERG gene fusions occur in about 50% of all prostate cancer cases
and represent promising markers for molecular subtyping. Although TMPRSS2-ERG fusion …

Overwhelming evidence indicates that cancer is a genetic disease caused by the
accumulation of mutations in oncogenes and tumor suppressor genes. It is also increasingly …

This work aimed to evaluate whether ETS transcription factors frequently involved in
rearrangements in prostate carcinomas (PCa), namely ERG and ETV1, regulate specific or …

To characterize the pattern of ETS rearrangements and to uncover novel ETS fusion genes,
we analyzed 200 prostate carcinomas (PCa) with TaqMan low‐density arrays (TLDAs) …

FLI1 and ERG, the major ETS transcription factors involved in rearrangements in the Ewing's
sarcoma family of tumors (ESFT) and in prostate carcinomas (PCa), respectively, belong to …

Background Cysteine-rich secretory protein 3 (CRISP3) emerges as a potential biomarker in
the study of many cancers, including cervical cancer (CC). This study aimed to analyze the …

The established prognostic factors associated with prostatic adenocarcinoma are the
Gleason score, pathological T staging and serum prostatic-specific antigen (PSA) level …