Although death is inevitable, individuals have long sought to alter the course of the ageing
process. Indeed, ageing has proved to be modifiable; by intervening in biological systems …

WNT signaling is an elaborate and complex collection of signal transduction pathways
mediated by multiple signaling molecules. WNT signaling is critically important for …

Mesenchymal stem cells have been used for cardiovascular regenerative therapy for
decades. These cells have been established as one of the potential therapeutic agents …

Identification of cost-effective interventions to maintain muscle mass, muscle strength, and
physical performance during muscle wasting and aging is an important public health …

Objective Wnt signaling pathway significantly participates in cardiac fibrosis and CFs
activation. Therefore, we reviewed current evidence on the new perspectives and biological …

Mesenchymal stem cells (MSCs) are multipotent precursor cells originating from several
adult connective tissues. MSCs possess the ability to self-renew and differentiate into …

Cardiovascular disease usually triggers coronary heart disease, stroke, and ischemic
diseases, thus promoting the development of functional failure. Mesenchymal stem cells …

The rupture of atherosclerotic plaques is essential for cardiovascular and cerebrovascular
events. Identification of the key genes related to plaque rupture is an important approach to …

Cell therapy has the potential to improve healing of ischemic heart, repopulate injured
myocardium and restore cardiac function. The tremendous hope and potential of stem cell …

Stem cell therapy is a promising approach to the treatment of ischemic heart disease via
replenishing cell loss after myocardial infarction. Both preclinical studies and clinical trials …