Catalytic enantioselective aldol reactions

Y Yamashita, T Yasukawa, WJ Yoo… - Chemical Society …, 2018 - pubs.rsc.org
Recent developments in catalytic asymmetric aldol reactions have been summarized.
Enantioselective aldol reactions are important methods to synthesize β-hydroxy carbonyl …

Catalytic Enantioselective Isocyanide‐Based Reactions: Beyond Passerini and Ugi Multicomponent Reactions

J Luo, GS Chen, SJ Chen, ZD Li… - Chemistry–A European …, 2021 - Wiley Online Library
The development of catalytic enantioselective isocyanide‐based reactions is currently of
great interest because the resulting products are valuable in organic synthesis …

Catalytic asymmetric [3+ 2] cycloaddition reaction between aurones and isocyanoacetates: Access to spiropyrrolines via silver catalysis

ZP Wang, S Xiang, PL Shao, Y He - The Journal of Organic …, 2018 - ACS Publications
The first enantioselective formal [3+ 2] cycloaddition of aurone analogues with
isocyanoacetates was developed via chiral Ag-complex catalysis. A variety of optically …

Enantioselective synthesis of 5-trifluoromethyl-2-oxazolines under dual silver/organocatalysis

P Martínez-Pardo, G Blay, C Vila… - The Journal of …, 2018 - ACS Publications
The first enantioselective formal [3+ 2] cycloaddition between α-isocyanoesters and
trifluoromethylketones to give 5-trifluoromethyl-2-oxazolines bearing two contiguous …

Enantioselective synthesis of chiral oxazolines from unactivated ketones and isocyanoacetate esters by synergistic silver/organocatalysis

P Martínez-Pardo, G Blay, MC Muñoz… - Chemical …, 2018 - pubs.rsc.org
A multicatalytic approach that combines a bifunctional Brønsted base–squaramide
organocatalyst and Ag+ as Lewis acid has been applied in the reaction of unactivated …

Recent advances in the chemistry of isocyanides with activated methylene group

IV Efimov, LN Kulikova, DI Zhilyaev… - European Journal of …, 2020 - Wiley Online Library
This review is devoted to the recent advances in the chemistry of methylene isocyanides
with C= C, C≡ C, C= O, and C= N bonds. In this paper, we show a variety of [3+ 2] …

One‐Pot Synthesis of 2‐(Alkylsulfanyl) quinolines from Aryl Isothiocyanates and Allenes or Alkynes

NA Nedolya, OA Tarasova, AV Artem'ev… - European Journal of …, 2024 - Wiley Online Library
In this work, a conceptually novel approach to diversely substituted 2‐(alkylsulfanyl)
quinolines is described. The approach includes the assembly of the target molecules from …

4-fluoro-threonine: From diastereoselective synthesis to pH-dependent conformational equilibrium in aqueous solution

S Potenti, L Spada, M Fusè, G Mancini, A Gualandi… - ACS …, 2021 - ACS Publications
4-Fluoro-threonine, the only fluoro amino acid of natural origin discovered so far, is an
interesting target for both synthetic and theoretical investigations. In this work, we lay the …

Five-Membered Ring Systems: With O and N Atoms

FM Cordero, D Giomi, L Lascialfari - Progress in Heterocyclic Chemistry, 2018 - Elsevier
This chapter discusses the five-membered ring systems with O & N atoms such as
isoxazoles, isoxazolines, isoxazolidines, oxazoles, oxazolines, oxazolidines, and …

[PDF][PDF] Enantioselective synthesis of five membered heterocycles through [3+ 2] Cycloadditions with Isocyano Esters

G Blay, C Vila, P Martínez-Pardo, JR Pedro - Targets Heterocycl. Syst, 2018 - soc.chim.it
The formal [3+ 2]-cycloaddition reaction of α-isocyano esters (isocyanoacetates) and
electrophilic double bonds provides a straightforward and atom economical access to five …