Amorphous solid dispersions: An update for preparation, characterization, mechanism on bioavailability, stability, regulatory considerations and marketed products
Amorphous solid dispersions (ASDs) are being employed frequently to improve
bioavailability of poorly soluble molecules by enhancing the rate and extant of dissolution in …
bioavailability of poorly soluble molecules by enhancing the rate and extant of dissolution in …
Structural modification aimed for improving solubility of lead compounds in early phase drug discovery
Many lead compounds fail to reach clinical trials despite being potent because of low
bioavailability attributed to their insufficient solubility making solubility a primary and crucial …
bioavailability attributed to their insufficient solubility making solubility a primary and crucial …
Preparation of a novel biodegradable packaging film based on corn starch-chitosan and poloxamers
A Fonseca-García, EJ Jiménez-Regalado… - Carbohydrate …, 2021 - Elsevier
Starch is an excellent alternative to produce packaging materials, however, due to its high
hydrophilicity, it is necessary to mix it with other polymers. Chitosan (CTS) is a polymer …
hydrophilicity, it is necessary to mix it with other polymers. Chitosan (CTS) is a polymer …
[HTML][HTML] Miscibility study of thermoplastic starch/polylactic acid blends: thermal and superficial properties
A Fonseca-García, BH Osorio, RY Aguirre-Loredo… - Carbohydrate …, 2022 - Elsevier
In this work, the miscibility of blends of thermoplastic Achira Starch (AS) and polylactic acid
(PLA) was evaluated, assisted by Pluronic® F127 an amphiphilic triblock copolymer that …
(PLA) was evaluated, assisted by Pluronic® F127 an amphiphilic triblock copolymer that …
A simple electrochemical detection of atorvastatin based on disposable screen-printed carbon electrodes modified by molecularly imprinted polymer: Experiment and …
P Rebelo, JG Pacheco, IV Voroshylova, A Melo… - Analytica Chimica …, 2022 - Elsevier
Atorvastatin (ATV) is a statin member consumed in high quantities worldwide. In response to
that, the occurrence of ATV in environmental waters has become a reality, highlighting the …
that, the occurrence of ATV in environmental waters has become a reality, highlighting the …
A novel sustained anti-inflammatory effect of atorvastatin—calcium PLGA nanoparticles: in vitro optimization and in vivo evaluation
Atorvastatin Calcium (At-Ca) has pleiotropic effect as anti-inflammatory drug beside its main
antihyperlipidemic action. Our study was conducted to modulate the anti-inflammatory effect …
antihyperlipidemic action. Our study was conducted to modulate the anti-inflammatory effect …
Tissue engineering and targeted drug delivery in cardiovascular disease: the role of polymer nanocarrier for statin therapy
N Montelione, F Loreni, A Nenna, V Catanese, L Scurto… - Biomedicines, 2023 - mdpi.com
Atherosclerosis-related coronary artery disease (CAD) is the leading cause of mortality and
morbidity worldwide. This requires effective primary and secondary prevention in reducing …
morbidity worldwide. This requires effective primary and secondary prevention in reducing …
Transparent silk fibroin film-facilitated infected-wound healing through antibacterial, improved fibroblast adhesion and immune modulation
J Zhang, L Wang, C Xu, Y Cao, S Liu… - Journal of Materials …, 2024 - pubs.rsc.org
The clinical application of regenerated silk fibroin (RSF) films for wound treatment is
restricted by its undesirable mechanical properties and lack of antibacterial activity. Herein …
restricted by its undesirable mechanical properties and lack of antibacterial activity. Herein …
Glucose oxidase loaded thermosensitive hydrogel as an antibacterial wound dressing
X Fang, Y Liu, M Zhang, S Zhou, P Cui, H Hu… - Journal of Drug Delivery …, 2022 - Elsevier
Skin infection is a worldwide issue that requires joint efforts to develop suitable wound
dressing. Hydrogel as the ideal form of wound dressing usually suffered from complicated …
dressing. Hydrogel as the ideal form of wound dressing usually suffered from complicated …
Polymers and nanoparticles for statin delivery: current use and future perspectives in cardiovascular disease
Atherosclerosis-related coronary artery disease (CAD) is one of the leading sources of
mortality and morbidity in the world. Primary and secondary prevention appear crucial to …
mortality and morbidity in the world. Primary and secondary prevention appear crucial to …