Neuroinflammation and oxidative stress in the pathogenesis of autism spectrum disorder
N Usui, H Kobayashi, S Shimada - International Journal of Molecular …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by
impairments in social communication, repetitive behaviors, restricted interests, and …
impairments in social communication, repetitive behaviors, restricted interests, and …
Noteworthy perspectives on microglia in neuropsychiatric disorders
H Zhu, A Guan, J Liu, L Peng, Z Zhang… - Journal of …, 2023 - Springer
Microglia are so versatile that they not only provide immune surveillance for central nervous
system, but participate in neural circuitry development, brain blood vessels formation, blood …
system, but participate in neural circuitry development, brain blood vessels formation, blood …
Role of Microglia in Central Nervous System Development and Plasticity
DP Schafer, B Stevens… - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
The nervous system comprises a remarkably diverse and complex network of cell types,
which must communicate with one another with speed, reliability, and precision. Thus, the …
which must communicate with one another with speed, reliability, and precision. Thus, the …
Fate mapping of Spp1 expression reveals age-dependent plasticity of disease-associated microglia-like cells after brain injury
Y Lan, X Zhang, S Liu, C Guo, Y Jin, H Li, L Wang… - Immunity, 2024 - cell.com
Microglial reactivity to injury and disease is emerging as a heterogeneous, dynamic, and
crucial determinant in neurological disorders. However, the plasticity and fate of disease …
crucial determinant in neurological disorders. However, the plasticity and fate of disease …
Modeling psychotic disorders: Environment x environment interaction
K Murlanova, MV Pletnikov - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Schizophrenia is a major psychotic disorder with multifactorial etiology that includes
interactions between genetic vulnerability and environmental risk factors. In addition …
interactions between genetic vulnerability and environmental risk factors. In addition …
On developmental programming of the immune system
JY Hong, R Medzhitov - Trends in Immunology, 2023 - cell.com
Early-life environmental exposures play a significant role in shaping long-lasting immune
phenotypes and disease susceptibility. Nevertheless, comprehensive understanding of the …
phenotypes and disease susceptibility. Nevertheless, comprehensive understanding of the …
Microbial modulation via cross-fostering prevents the effects of pervasive environmental stressors on microglia and social behavior, but not the dopamine system
Environmental toxicant exposure, including air pollution, is increasing worldwide. However,
toxicant exposures are not equitably distributed. Rather, low-income and minority …
toxicant exposures are not equitably distributed. Rather, low-income and minority …
The role of microglia in early neurodevelopment and the effects of maternal immune activation
LJM Mastenbroek, SM Kooistra, BJL Eggen… - Seminars in …, 2024 - Springer
Activation of the maternal immune system during gestation has been associated with an
increased risk for neurodevelopmental disorders in the offspring, particularly schizophrenia …
increased risk for neurodevelopmental disorders in the offspring, particularly schizophrenia …
[HTML][HTML] Maternal BPAF exposure impaired synaptic development and caused behavior abnormality in offspring
X Wu, S Li, Y Ni, C Qi, S Bai, Q Xu, Y Fan, X Ma… - Ecotoxicology and …, 2023 - Elsevier
Bisphenol A (BPA) has been widely restricted, leading to a significant increase in the
production of bisphenol AF (BPAF), one of the most common bisphenol analogs use as a …
production of bisphenol AF (BPAF), one of the most common bisphenol analogs use as a …
SSRI treatment modifies the effects of maternal inflammation on in utero physiology and offspring neurobiology
KE Zengeler, DA Shapiro, KR Bruch… - Brain, behavior, and …, 2023 - Elsevier
Perturbations to the in utero environment can dramatically change the trajectory of offspring
neurodevelopment. Insults commonly encountered in modern human life such as infection …
neurodevelopment. Insults commonly encountered in modern human life such as infection …