Plant metabolomics: large-scale phytochemistry in the functional genomics era

LW Sumner, P Mendes, RA Dixon - Phytochemistry, 2003 - Elsevier
Metabolomics or the large-scale phytochemical analysis of plants is reviewed in relation to
functional genomics and systems biology. A historical account of the introduction and …

Predicting function: from genes to genomes and back

P Bork, T Dandekar, Y Diaz-Lazcoz… - Journal of molecular …, 1998 - Elsevier
Predicting function from sequence using computational tools is a highly complicated
procedure that is generally done for each gene individually. This review focuses on the …

The small world inside large metabolic networks

A Wagner, DA Fell - Proceedings of the Royal Society of …, 2001 - royalsocietypublishing.org
The metabolic network of the catabolic, energy and biosynthetic metabolism of Escherichia
coli is a paradigmatic case for the large genetic and metabolic networks that functional …

Dividing the large glycoside hydrolase family 13 into subfamilies: towards improved functional annotations of α-amylase-related proteins

MR Stam, EGJ Danchin, C Rancurel… - Protein Engineering …, 2006 - academic.oup.com
Family GH13, also known as the α-amylase family, is the largest sequence-based family of
glycoside hydrolases and groups together a number of different enzyme activities and …

[图书][B] Natural products from plants

LJ Cseke, A Kirakosyan, PB Kaufman, S Warber… - 2016 - api.taylorfrancis.com
2008 NOMINEE The Council on Botanical and Horticultural Libraries Annual Award for a
Significant Work in Botanical or Horticultural Literature From medicinal, industrial, and …

The small world of metabolism

DA Fell, A Wagner - Nature biotechnology, 2000 - nature.com
Of course, metabolism might have evolved small-world characteristics to optimize metabolic
function in some way. Watts and Strogatz17 have studied how fast perturbations spread …

Computation with the KEGG pathway database

H Ogata, S Goto, W Fujibuchi, M Kanehisa - Biosystems, 1998 - Elsevier
We introduce and discuss a new computational approach towards prediction and inference
of biological functions from genomic sequences by making use of the pathway data in …

Subnetwork hierarchies of biochemical pathways

P Holme, M Huss, H Jeong - Bioinformatics, 2003 - academic.oup.com
Motivation: The vastness and complexity of the biochemical networks that have been
mapped out by modern genomics calls for decomposition into subnetworks. Such networks …

Microbial genome analyses: global comparisons of transport capabilities based on phylogenies, bioenergetics and substrate specificities

IT Paulsen, MK Sliwinski, MH Saier Jr - Journal of molecular biology, 1998 - Elsevier
We have conducted genome sequence analyses of seven prokaryotic microorganisms for
which completely sequenced genomes are available (Escherichia coli, Haemophilus …

Metabolic modeling of microbial strains in silico

MW Covert, CH Schilling, I Famili, JS Edwards… - Trends in biochemical …, 2001 - cell.com
The large volume of genome-scale data that is being produced and made available in
databases on the World Wide Web is demanding the development of integrated …