Dietary fructose and fructose-induced pathologies

S Jung, H Bae, WS Song, C Jang - Annual review of nutrition, 2022 - annualreviews.org
The consumption of fructose as sugar and high-fructose corn syrup has markedly increased
during the past several decades. This trend coincides with the exponential rise of metabolic …

Epigenetics in NAFLD/NASH: Targets and therapy

N Sodum, G Kumar, SL Bojja, N Kumar… - Pharmacological …, 2021 - Elsevier
Recently non-alcoholic fatty liver disease (NAFLD) has grabbed considerable scientific
attention, owing to its rapid increase in prevalence worldwide and growing burden on end …

Non-alcoholic fatty liver disease (NAFLD), type 2 diabetes, and non-viral hepatocarcinoma: Pathophysiological mechanisms and new therapeutic strategies

E Vetrano, L Rinaldi, A Mormone, C Giorgione… - Biomedicines, 2023 - mdpi.com
In recent years, the incidence of non-viral hepatocellular carcinoma (HCC) has increased
dramatically, which is probably related to the increased prevalence of metabolic syndrome …

Chinese herbal medicines: The modulator of nonalcoholic fatty liver disease targeting oxidative stress

P Gong, H Long, Y Guo, Z Wang, W Yao, J Wang… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Plants are a natural treasure trove; their secondary
metabolites participate in several pharmacological processes, making them a crucial …

The role of probiotics in nonalcoholic fatty liver disease: a new insight into therapeutic strategies

M Meroni, M Longo, P Dongiovanni - Nutrients, 2019 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) encompasses a broad spectrum of pathological
hepatic conditions ranging from simple steatosis to nonalcoholic steatohepatitis (NASH) …

Nonalcoholic fatty liver disease is exacerbated in high-fat diet-fed gnotobiotic mice by colonization with the gut microbiota from patients with nonalcoholic …

CC Chiu, YH Ching, YP Li, JY Liu, YT Huang… - Nutrients, 2017 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is a serious liver disorder associated with the
accumulation of fat and inflammation. The objective of this study was to determine the gut …

Breaking the barriers: the role of gut homeostasis in Metabolic-Associated Steatotic Liver Disease (MASLD)

R Benedé-Ubieto, FJ Cubero, YA Nevzorova - Gut microbes, 2024 - Taylor & Francis
ABSTRACT Obesity, insulin resistance (IR), and the gut microbiome intricately interplay in
Metabolic-associated Steatotic Liver Disease (MASLD), previously known as Non-Alcoholic …

Microbiome dysbiosis: a pathological mechanism at the intersection of obesity and glaucoma

S Pezzino, M Sofia, LP Greco, G Litrico… - International Journal of …, 2023 - mdpi.com
The rate at which obesity is becoming an epidemic in many countries is alarming. Obese
individuals have a high risk of developing elevated intraocular pressure and glaucoma …

Intestinal microbiota modulation in obesity-related non-alcoholic fatty liver disease

D Porras, E Nistal, S Martínez-Flórez… - Frontiers in …, 2018 - frontiersin.org
Obesity and associated comorbidities, including non-alcoholic fatty liver disease (NAFLD),
are a major concern to public well-being worldwide due to their high prevalence among the …

The role of bile acids in metabolic regulation

L Vítek, M Haluzík - Journal of endocrinology, 2016 - joe.bioscientifica.com
Bile acids (BA), long believed to only have lipid-digestive functions, have emerged as novel
metabolic modulators. They have important endocrine effects through multiple cytoplasmic …