The thyroid hormones are very hydrophobic and those that exhibit biological activity are 3′,
5′, 3, 5-L-tetraiodothyronine (T4), 3′, 5, 3-L-triiodothyronine (T3), 3′, 5′, 3-L …

The head kidney, analogous to the mammalian adrenal gland, is an organ unique for teleost
fish. It comprises cytokine-producing lymphoid cells from the immune system and endocrine …

The slow clearance, prolonged half-life, and high serum concentration of thyroxine (T4) are
largely due to strong binding by the principal plasma thyroid hormone-binding proteins …

Thyroid hormones control growth, development, differentiation and metabolism in
vertebrates. Most of the actions of the active thyroid hormone T3 (3, 5, 3′-triiodo-l …

Transthyretin (TTR) belongs to a group of proteins, which includes thyroxine-binding
globulin and albumin, that bind to and transport thyroid hormones in the blood. TTR is also …

ABBREVIATIONS FAP FAMILIAL AMYLOIDOTIC POLYNELJROP4Tm SSCP SZNGLE
STRAND CONFORMATlON POLYMORPHISMS AS0 ALLELE SPECIFIC …

Familial amyloidotic polyneuropathy (FAP) is an inherited autosomal dominant disease that
is commonly caused by accumulation of deposits of transthyretin (TTR) amyloid around …

Thyroxine, the most abundant thyroid hormone in blood, partitions into lipid membranes. In a
network-like system, thyroxine-binding plasma proteins counteract this partitioning and …

We examined the effects of industrial, medical and agricultural chemicals on 3, 5, 3′-l-[125I]
triiodothyronine ([125I] T3) binding to transthyretins (TTRs) and thyroid hormone receptors …

In larger mammals, thyroid hormone-binding plasma proteins are albumin, transthyretin
(TTR) and thyroxine (T4)-binding globulin. They differ characteristically in affinities and …