Ethnobotany and the role of plant natural products in antibiotic drug discovery
The crisis of antibiotic resistance necessitates creative and innovative approaches, from
chemical identification and analysis to the assessment of bioactivity. Plant natural products …
chemical identification and analysis to the assessment of bioactivity. Plant natural products …
Natural products against key Mycobacterium tuberculosis enzymatic targets: Emerging opportunities for drug discovery
G Cazzaniga, M Mori, LR Chiarelli, A Gelain… - European journal of …, 2021 - Elsevier
For centuries, natural products (NPs) have served as powerful therapeutics against a variety
of human ailments. Nowadays, they still represent invaluable resources for the treatment of …
of human ailments. Nowadays, they still represent invaluable resources for the treatment of …
Bactericidal Activity of Larrea tridentata Hydroalcoholic Extract against Phytopathogenic Bacteria
AL Morales-Ubaldo, N Rivero-Perez, F Avila-Ramos… - Agronomy, 2021 - mdpi.com
Due to the emergence of bacterial resistance in phytopathogenic microorganisms, it is
necessary to search for new treatment alternatives for these pathogens. Natural extracts are …
necessary to search for new treatment alternatives for these pathogens. Natural extracts are …
Phytochemical Compounds and Pharmacological Properties of Larrea tridentata
AL Morales-Ubaldo, N Rivero-Perez… - Molecules, 2022 - mdpi.com
For centuries, traditional medicine from plants (phytotherapy) was the only treatment for
infectious and non-infectious diseases. Although it is still practiced in several countries with …
infectious and non-infectious diseases. Although it is still practiced in several countries with …
nor 3′-Demethoxyisoguaiacin from Larrea tridentata Is a Potential Alternative against Multidrug-Resistant Bacteria Associated with Bovine Mastitis
AL Morales-Ubaldo, M Gonzalez-Cortazar… - Molecules, 2022 - mdpi.com
Bovine mastitis is one of the most common diseases in dairy cows, and it causes significant
economic losses in dairy industries worldwide. Gram-positive and Gram-negative bacteria …
economic losses in dairy industries worldwide. Gram-positive and Gram-negative bacteria …
[HTML][HTML] Nordihydroguaiaretic acid (NDGA) and α-mangostin inhibit the growth of Mycobacterium tuberculosis by inducing autophagy
S Guzmán-Beltrán, MÁ Rubio-Badillo, E Juárez… - International …, 2016 - Elsevier
Tuberculosis (TB) remains as a global health problem. The prevalence of this infection is
related to the association with other diseases, such as HIV, neglect treatment and misuse of …
related to the association with other diseases, such as HIV, neglect treatment and misuse of …
Context-specific metabolic network reconstruction of a naphthalene-degrading bacterial community guided by metaproteomic data
L Tobalina, R Bargiela, J Pey, FA Herbst, I Lores… - …, 2015 - academic.oup.com
Motivation: With the advent of meta-'omics' data, the use of metabolic networks for the
functional analysis of microbial communities became possible. However, while network …
functional analysis of microbial communities became possible. However, while network …
New cyclolignans of Larrea tridentata and their antibacterial and cytotoxic activities
G Núñez-Mojica, AL Vázquez-Ramírez, A García… - Phytochemistry …, 2021 - Elsevier
From the chloroform extract of Larrea tridentata (Ses. et Moc ex DC.) Coville two new
cyclolignans (1 and 2) and six known compounds (3–8) were isolated and characterized …
cyclolignans (1 and 2) and six known compounds (3–8) were isolated and characterized …
Antimycobacterial mechanism of vanillin involves disruption of cell-surface integrity, virulence attributes, and iron homeostasis
S Sharma, R Pal, S Hameed… - The International Journal of …, 2016 - journals.lww.com
Methods: Drug susceptibilities were performed using broth microdilution, spot, and filter-disc
assays. Membrane damage was studied by nitrocefin hydrolysis and electron microscopy …
assays. Membrane damage was studied by nitrocefin hydrolysis and electron microscopy …
meso-Dihydroguaiaretic acid derivatives with antibacterial and antimycobacterial activity
K Reyes-Melo, A García, A Romo-Mancillas… - Bioorganic & Medicinal …, 2017 - Elsevier
Thirty-three meso-dihydroguaiaretic acid (meso-DGA) derivatives bearing esters, ethers,
and amino-ethers were synthesized. All derivatives were tested against twelve drug …
and amino-ethers were synthesized. All derivatives were tested against twelve drug …