Digital twins in pharmaceutical and biopharmaceutical manufacturing: a literature review
The development and application of emerging technologies of Industry 4.0 enable the
realization of digital twins (DT), which facilitates the transformation of the manufacturing …
realization of digital twins (DT), which facilitates the transformation of the manufacturing …
[HTML][HTML] Process analytical technologies–advances in bioprocess integration and future perspectives
G Gerzon, Y Sheng, M Kirkitadze - Journal of pharmaceutical and …, 2022 - Elsevier
Abstract Process Analytical Technology (PAT) instruments include analyzers capable of
measuring physical and chemical process parameters and key attributes with the goal of …
measuring physical and chemical process parameters and key attributes with the goal of …
Paper electrode-based flexible pressure sensor for point-of-care immunoassay with digital multimeter
Z Yu, Y Tang, G Cai, R Ren, D Tang - Analytical chemistry, 2018 - ACS Publications
A novel paper electrode-based flexible pressure sensor modified with multiwalled carbon
nanotubes was designed for point-of-care (POC) immunoassay of carcinoembryonic antigen …
nanotubes was designed for point-of-care (POC) immunoassay of carcinoembryonic antigen …
Bioprocess control: current progress and future perspectives
Typical bioprocess comprises of different unit operations wherein a near optimal
environment is required for cells to grow, divide, and synthesize the desired product …
environment is required for cells to grow, divide, and synthesize the desired product …
Modern sensor tools and techniques for monitoring, controlling, and improving cell culture processes
SJ Reyes, Y Durocher, PL Pham, O Henry - Processes, 2022 - mdpi.com
The growing biopharmaceutical industry has reached a level of maturity that allows for the
monitoring of numerous key variables for both process characterization and outcome …
monitoring of numerous key variables for both process characterization and outcome …
Towards smart biomanufacturing: a perspective on recent developments in industrial measurement and monitoring technologies for bio-based production processes
CL Gargalo, I Udugama, K Pontius… - Journal of Industrial …, 2020 - academic.oup.com
The biomanufacturing industry has now the opportunity to upgrade its production processes
to be in harmony with the latest industrial revolution. Technology creates capabilities that …
to be in harmony with the latest industrial revolution. Technology creates capabilities that …
Blueprints for biosensors: design, limitations, and applications
Biosensors are enabling major advances in the field of analytics that are both facilitating and
being facilitated by advances in synthetic biology. The ability of biosensors to rapidly and …
being facilitated by advances in synthetic biology. The ability of biosensors to rapidly and …
[HTML][HTML] Automation and artificial intelligence in filamentous fungi-based bioprocesses: A review
S Wainaina, MJ Taherzadeh - Bioresource Technology, 2023 - Elsevier
By utilizing their powerful metabolic versatility, filamentous fungi can be utilized in
bioprocesses aimed at achieving circular economy. With the current digital transformation …
bioprocesses aimed at achieving circular economy. With the current digital transformation …
Process analytical technologies and data analytics for the manufacture of monoclonal antibodies
MK Maruthamuthu, SR Rudge, AM Ardekani… - Trends in …, 2020 - cell.com
Process analytical technology (PAT) for the manufacture of monoclonal antibodies (mAbs) is
defined by an integrated set of advanced and automated methods that analyze the …
defined by an integrated set of advanced and automated methods that analyze the …
Challenges in the development of soft sensors for bioprocesses: A critical review
Among the greatest challenges in soft sensor development for bioprocesses are variable
process lengths, multiple process phases, and erroneous model inputs due to sensor faults …
process lengths, multiple process phases, and erroneous model inputs due to sensor faults …