Obesity has become a major public health issue in China. Overweight and obesity have
increased rapidly in the past four decades, and the latest national prevalence estimates for …

Epidemiologic and clinical research has provided a large body of evidence supporting the
developmental origins of health and disease (DOHaD), but there has been a relative dearth …

The molecular signatures of epigenetic regulation and chromatin architectures are
fundamental to genetically determined biological processes. Covalent and post-translational …

Introduction Child malnutrition (undernutrition) and adult non-communicable diseases
(NCDs) are major global public health problems. While convincing evidence links prenatal …

Abstract Background Most Chinese people over 55 years old today have experienced the
Great Leap Forward Famine of 1959–61. Many reports suggested that the famine could …

The gene–environment interactions resulting from famine and the subsequent increased
intergenerational risk of type 2 diabetes mellitus (T2DM) have contributed to the current …

Death rates over the following 2 decades corresponded closely with alcohol control policies
and regulation. 3 In particular, policies introduced in 2006 and in the following years led to …

Chronic hyperglycemia statue noticed in diabetes mellitus favors the manifestation of
oxidative stress by increasing the production of reactive oxygen species and/or by reducing …

The developmental origins hypothesis proposes that undernutrition during early
development is associated with an increased type 2 diabetes risk in adulthood. We …

Background The short-and medium-term effects of conflict on population health are
reasonably well documented. Less considered are its consequences across generations …