[HTML][HTML] Monocarboxylate transporters in the brain and in cancer

J Pérez-Escuredo, VF Van Hée, M Sboarina… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Monocarboxylate transporters (MCTs) constitute a family of 14 members among which
MCT1–4 facilitate the passive transport of monocarboxylates such as lactate, pyruvate and …

[PDF][PDF] Monocarboxylic acid transport

AP Halestrap - Compr Physiol, 2013 - scholar.archive.org
Monocarboxylates such as lactate, pyruvate, and the ketone bodies play major roles in
metabolism and must be transported across both the plasma membrane and mitochondrial …

Butyrate and colorectal cancer: the role of butyrate transport

P Goncalves, F Martel - Current drug metabolism, 2013 - ingentaconnect.com
Colorectal cancer (CRC) is one of the most common solid tumors worldwide. A diet rich in
dietary fiber is associated with a reduction in its risk. Butyrate (BT) is one of the main end …

Transport of ketone bodies and lactate in the sheep ruminal epithelium by monocarboxylate transporter 1

F Muller, K Huber, H Pfannkuche… - American Journal …, 2002 - journals.physiology.org
Due to intensive intracellular metabolism of short-chain fatty acids, ruminal epithelial cells
generate large amounts of d-β-hydroxybutyric acid, acetoacetic acid, and lactic acid. These …

Lithium: a promising anticancer agent

EY Villegas-Vázquez, LI Quintas-Granados, H Cortés… - Life, 2023 - mdpi.com
Lithium is a therapeutic cation used to treat bipolar disorders but also has some important
features as an anti-cancer agent. In this review, we provide a general overview of lithium …

[HTML][HTML] Regulation of colonic epithelial butyrate transport: Focus on colorectal cancer

P Goncalves, F Martel - Porto Biomedical Journal, 2016 - Elsevier
Colorectal cancer (CRC) is one of the most common solid tumors worldwide. Consumption
of dietary fiber is associated with a low risk of developing CRC. The fermentation of the …

Enteric and systemic postprandial lactate shuttle phases and dietary carbohydrate carbon flow in humans

RG Leija, CC Curl, JA Arevalo, AD Osmond… - Nature …, 2024 - nature.com
Dietary glucose in excess is stored in the liver in the form of glycogen. As opposed to direct
conversion of glucose into glycogen, the hypothesis of the postprandial lactate shuttle (PLS) …

[HTML][HTML] Intestinal OCTN2-and MCT1-targeted drug delivery to improve oral bioavailability

G Wang, L Zhao, Y Sun, D Zhao, M Sun, Z He… - Asian Journal of …, 2020 - Elsevier
Various drug transporters are widely expressed throughout the intestine and play important
roles in absorbing nutrients and drugs, thus providing high quality targets for the design of …

Role of monocarboxylic acid transporters in the cellular uptake of NSAIDs

JS Choi, MJ Jin, HK Han - Journal of Pharmacy and …, 2005 - academic.oup.com
The present study investigated the cellular uptake mechanism of non-steroidal anti-
inflammatory drugs (NSAIDs) in Caco-2 cells. Diflunisal, diclofenac, ketoprofen and …

[HTML][HTML] Characterization of the segmental transport mechanisms of DL-methionine hydroxy analogue along the intestinal tract of rainbow trout with an additional …

M Subramaniam, K Masagounder… - … and Physiology Part A …, 2020 - Elsevier
The aim of this study was to identify the unknown transport mechanism of the extensively
used monocarboxylate methionine feed supplement DL-methionine hydroxy analogue (DL …