Role of reactive oxygen species and mitochondrial damage in rheumatoid arthritis and targeted drugs

W Jing, C Liu, C Su, L Liu, P Chen, X Li… - Frontiers in …, 2023 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial
inflammation, pannus formation, and bone and cartilage damage. It has a high disability …

Ferroptosis as an emerging target in rheumatoid arthritis

H Zhao, C Tang, M Wang, H Zhao, Y Zhu - Frontiers in Immunology, 2023 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology. Due to the rise in
the incidence rate of RA and the limitations of existing therapies, the search for new …

Periplogenin inhibits pathologic synovial proliferation and infiltration in rheumatsuoid arthritis by regulating the JAK2/3-STAT3 pathway

X Zhong, W Feng, L Liu, Q Liu, Q Xu, M Liu… - International …, 2024 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disease that affects joints, causing
inflammation, synovitis, and erosion of cartilage and bone. Periplogenin is an active …

Metabolic Effects of Anti-TNF-α Treatment in Rheumatoid Arthritis

K Macáková, M Tekeľová, V Mlynáriková, K Šebeková… - Diseases, 2023 - mdpi.com
Rheumatoid arthritis (RA) is associated with high cardiovascular mortality. It is not clear
whether the metabolic consequences of chronic inflammation are involved. Biological …

Recent advances on neutrophil dysregulation in the pathogenesis of rheumatic diseases

J Chen, X Wang, Y Liu, X Zhang - Current Opinion in …, 2024 - journals.lww.com
Recent advances have significantly reinforced the crucial role of neutrophil dysregulation in
the pathogenesis of RMD. A deeper understanding of the potential mechanisms underlying …

[HTML][HTML] Exploration of the molecular mechanism guiding Xinfeng capsule regulatory mechanism for rheumatoid arthritis inflammation

Z Zhu, L Wan - American Journal of Translational Research, 2024 - ncbi.nlm.nih.gov
Objectives: Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic
inflammation of the joint synovium. The traditional Chinese medicine Xinfeng capsule (XFC) …

Prodrug-based nanomedicines for rheumatoid arthritis

P Li, C Wang, H Huo, C Xu, H Sun, X Wang, L Wang… - Discover Nano, 2024 - Springer
Most antirheumatic drugs with high toxicity exhibit a narrow therapeutic window due to their
nonspecific distribution in the body, leading to undesirable side effects and reduced patient …

[PDF][PDF] Discover Nano

C Liu, S To, X Sheng, R Wang, J Xu - 2023 - d-nb.info
Ischemic stroke is one of the most severe neurological disorders with limited therapeutic
strategies. The utilization of nanoparticle drug delivery systems is a burgeoning field and …