Comprehensive analyses of bioinformatics applications in the fight against COVID-19 pandemic

L Ma, H Li, J Lan, X Hao, H Liu, X Wang… - … biology and chemistry, 2021 - Elsevier
Abstract Novel coronavirus disease 2019 (COVID-19) is a global pandemic caused by
severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), which can be …

Network for network concept offers new insights into host-SARS-CoV-2 protein interactions and potential novel targets for developing antiviral drugs

N Eskandarzade, A Ghorbani, S Samarfard… - Computers in biology …, 2022 - Elsevier
Abstract SARS-CoV-2, the causal agent of COVID-19, is primarily a pulmonary virus that can
directly or indirectly infect several organs. Despite many studies carried out during the …

Dynamics of SARS-CoV-2 spike proteins in cell entry: control elements in the amino-terminal domains

E Qing, T Kicmal, B Kumar, GM Hawkins, E Timm… - MBio, 2021 - Am Soc Microbiol
Selective pressures drive adaptive changes in the coronavirus spike proteins directing virus-
cell entry. These changes are concentrated in the amino-terminal domains (NTDs) and the …

Outbreaks of SARS-CoV-2 in naturally infected mink farms: Impact, transmission dynamics, genetic patterns, and environmental contamination

SC Chaintoutis, Z Thomou, E Mouchtaropoulou… - PLoS …, 2021 - journals.plos.org
SARS-CoV-2 infection outbreaks in minks have serious implications associated with animal
health and welfare, and public health. In two naturally infected mink farms (A and B) located …

An integrated understanding of the evolutionary and structural features of the SARS-CoV-2 spike receptor binding domain (RBD)

D Sanyal, S Banerjee, A Bej, VR Chowdhury… - International Journal of …, 2022 - Elsevier
Conventional drug development strategies typically use pocket in protein structures as drug-
target sites. They overlook the plausible effects of protein evolvability and resistant mutations …

Strategy to develop broadly effective multivalent COVID-19 vaccines against emerging variants based on Ad5/35 platform

S Chang, KS Shin, B Park, S Park… - Proceedings of the …, 2024 - National Acad Sciences
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron strain has
evolved into highly divergent variants with several sub-lineages. These newly emerging …

Highlight of potential impact of new viral genotypes of SARS-CoV-2 on vaccines and anti-viral therapeutics

A Ghorbani, S Samarfard, M Jajarmi, M Bagheri… - Gene Reports, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of the
coronavirus disease (COVID-19) pandemic, has infected millions of people globally. Genetic …

[HTML][HTML] Whole-genome sequencing of foot-and-mouth disease virus serotype O/PanAsia-2/QOM-15 and comparison of its VP1-encoding region with two vaccine …

M Gadir, SM Azimi, N Harzandi, B Hemati… - Veterinary Research …, 2023 - ncbi.nlm.nih.gov
Despite widespread vaccination against foot-and-mouth disease, many outbreaks still occur
in endemic areas. We attempted to determine the genetic and antigenic properties of the …

[HTML][HTML] Role of wild and domesticated animals in the origin and transmission of the coronavirus sars-cov-2

R Siala, A Mehdi - Бюллетень науки и практики, 2021 - cyberleninka.ru
The review highlights animal coronaviruses, their pathogenicity, and the possible role of
domestic and agricultural animals in the further spread of the COVID-19. Joint researches …

Diagnóstico de maturidade e ações para implementação de cultura voltada para sustentabilidade em empresa do setor de energia elétrica

KRS Silva - 2023 - repositorio.ufrn.br
Apesar da existência de sistemas de gestão da segurança, saúde e meio ambiente bem
estruturados em grandes organizações, os altos índices de acidentes ambientais continuam …