Recent studies of nitrogen containing heterocyclic compounds as novel antiviral agents: A review

A Mermer, T Keles, Y Sirin - Bioorganic Chemistry, 2021 - Elsevier
N-heterocycles are important, not only because of their abundance, but above all because of
their chemical, biological and technical significance. They play an important role in …

Recent advances in triazoles as tyrosinase inhibitors

A Mermer, S Demirci - European Journal of Medicinal Chemistry, 2023 - Elsevier
The tyrosinase enzyme, which is widely found in microorganisms, animals and plants, has a
significant position in melanogenesis, plays an important role in undesirable browning of …

An overview of 1, 2, 3-triazole-containing hybrids and their potential anticholinesterase activities

SA Khan, MJ Akhtar, U Gogoi, DU Meenakshi, A Das - Pharmaceuticals, 2023 - mdpi.com
Acetylcholine (ACh) neurotransmitter of the cholinergic system in the brain is involved in
learning, memory, stress responses, and cognitive functioning. It is hydrolyzed into choline …

Recent advances in the synthetic and medicinal perspective of quinolones: A review

P Dhiman, N Arora, PV Thanikachalam, V Monga - Bioorganic Chemistry, 2019 - Elsevier
In the modern scenario, the quinolone scaffold has emerged as a very potent motif
considering its clinical significance. Quinolones possess wide range of pharmacological …

Triazole derivatives as inhibitors of Alzheimer's disease: current developments and structure-activity relationships

M Xu, Y Peng, L Zhu, S Wang, J Ji… - European journal of …, 2019 - Elsevier
Alzheimer's disease (AD) is a well known neurodegenerative disorder alarming millions of
people worldwide and the subsequent epidemiological statistics highlights the implication of …

Transition metal complexes of a multidentate Schiff base ligand containing pyridine: synthesis, characterization, enzyme inhibitions, antioxidant properties, and …

E Bursal, F Turkan, K Buldurun, N Turan, A Aras… - Biometals, 2021 - Springer
A series of Fe (II), Ni (II), and Pd (II) complexes were prepared with a novel Schiff base
ligand containing pyridine moiety. The prepared compounds were characterized using FT …

Synthesis of novel Schiff bases using green chemistry techniques; antimicrobial, antioxidant, antiurease activity screening and molecular docking studies

A Mermer, N Demirbas, H Uslu, A Demirbas… - Journal of Molecular …, 2019 - Elsevier
Schiff base derivatives were synthesized in this study via conventional, microwave
irradiation and ultrasound sonication methods. Optimization conditions were examined for …

Synthesis, characterization, DFT calculation, antioxidant activity, ADMET and molecular docking of thiosemicarbazide derivatives and their Cu (II) complexes

A Mermer, S Alyar - Chemico-Biological Interactions, 2022 - Elsevier
In this work, new thiosemicarbazides (ECA-1, ECA-2) and their Cu (II) complexes (ECA-1-
Cu, ECA-2-Cu) were synthesized and their structures were characterized by 1 H NMR, 13 C …

Antioxidant activity of 1, 2, 4-triazole and its derivatives: A mini-review

A Pachuta-Stec - Mini reviews in medicinal chemistry, 2022 - ingentaconnect.com
The information about the presence of free radicals in biological materials was given for the
first time about 70 years ago. Since then, numerous scientific studies have been conducted …

Piperazine-azole-fluoroquinolone hybrids: Conventional and microwave irradiated synthesis, biological activity screening and molecular docking studies

A Mermer, O Faiz, A Demirbas, N Demirbas… - Bioorganic …, 2019 - Elsevier
Abstract A series of new 1, 2, 4-triazole and 1, 3, 4-oxadiazole derivatives was obtained via
several steps sequential reactions of phenyl piperazine. Then, these compounds were …