Myasthenia gravis (MG) is an autoimmune disorder caused by autoantibodies that target the
neuromuscular junction, leading to muscle weakness and fatigability. Currently available …

Recent structural studies of receptor tyrosine kinases (RTKs) have revealed unexpected
diversity in the mechanisms of their activation by growth factor ligands. Strategies for …

Neuromuscular synapse formation requires a complex exchange of signals between motor
neurons and skeletal muscle fibers, leading to the accumulation of postsynaptic proteins …

Receptor tyrosine kinases (RTKs) are essential components of signal transduction pathways
that mediate cell-to-cell communication. These single-pass transmembrane receptors, which …

Myasthenia gravis (MG) is a severely debilitating autoimmune disease that is due to a
decrease in the efficiency of synaptic transmission at neuromuscular synapses. MG is …

Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction (NMJ).
Autoantibodies target key molecules at the NMJ, such as the nicotinic acetylcholine receptor …

Muscle-specific kinase (MuSK) is essential for each step in neuromuscular synapse
formation. Before innervation, MuSK initiates postsynaptic differentiation, priming the muscle …

Neuromuscular synapse formation depends upon coordinated interactions between motor
neurons and muscle fibers, leading to the formation of a highly specialized postsynaptic …

The neuromuscular junction (NMJ) is the most extensively studied model of neuronal
synaptogenesis. Acetylcholine receptor (AChR) clustering on the postsynaptic membrane is …

MuSK is a receptor tyrosine kinase (RTK) that plays essential roles in the formation and
maintenance of the neuromuscular junction. Distinct from most members of RTK family …