Polycystic ovary syndrome (PCOS), one of the important endocrine disorders affecting
females in the reproductive age, is caused mainly by an abnormal oxidation status that …

The oocyte quality remains as one of the major problems associated with poor in vitro
fertilization (IVF) rate and assisted reproductive technology (ART) failure worldwide. The …

Aging processes accelerate dramatically in oocytes that have reached the metaphase-II (M-
II) stage. The present work aimed to study the patterns and intracellular pathways of actions …

It has been established that embryogenesis is accompanied by the intense production of
nitric oxide (NO). Based on available data, the rate of NO production is roughly equal in all …

The roles of cyclic guanosine monophosphate (cGMP) signaling in oocyte maturation
attracts much attention in mammals, but its roles in fish are still largely unknown. Using …

Oxidative stress causes several diseases and dysfunctions in cells, including oocytes.
Clearly, oxidative stress influences oocyte quality during in vitro maturation and fertilization …

Background Disruption of gap junction and transfer of cyclic nucleotides to the oocyte lead to
meiotic exit from diplotene arrest (EDA) in mammals. In the present study, we examined …

Objective The aim of our study was to detect a biomarker for selection of competent oocytes
with acceptable fertilization potential. Calcium ion fluctuation play the most critical role of …

Infertility is a major global health issue, affecting approximately 9% of couples worldwide. Its
prevalence increased steadily over the preceding decades, paralleling environmental and …

Nitric oxides (NO) act as one of the major signal molecules and modulate various cell
functions including oocyte meiosis in mammals. The present study was designed to …