Stability dynamics of neurofilament and GFAP networks and protein fragments

CL Phillips, M Faridounnia, D Armao… - Current Opinion in Cell …, 2023 - Elsevier
Neurofilaments (NFs) and GFAP are cytoskeletal intermediate filaments (IFs) that support
cellular processes unfolding within the uniquely complex environments of neurons and …

Ubiquitin system mutations in neurological diseases

C Zenge, A Ordureau - Trends in Biochemical Sciences, 2024 - Elsevier
Neuronal ubiquitin balance impacts the fate of countless cellular proteins, and its disruption
is associated with various neurological disorders. The ubiquitin system is critical for proper …

[HTML][HTML] Novel Approaches to Studying SLC13A5 Disease

AS Beltran - Metabolites, 2024 - mdpi.com
The role of the sodium citrate transporter (NaCT) SLC13A5 is multifaceted and context-
dependent. While aberrant dysfunction leads to neonatal epilepsy, its therapeutic inhibition …