Anti-microbial activity of phytocannabinoids and endocannabinoids in the light of their physiological and pathophysiological roles
RV Sionov, D Steinberg - Biomedicines, 2022 - mdpi.com
Antibiotic resistance has become an increasing challenge in the treatment of various
infectious diseases, especially those associated with biofilm formation on biotic and abiotic …
infectious diseases, especially those associated with biofilm formation on biotic and abiotic …
Gut microbiota modulates neurotransmitter and gut-brain signaling
S Qu, Z Yu, Y Zhou, S Wang, M Jia, T Chen… - Microbiological …, 2024 - Elsevier
Abstract Neurotransmitters, including 5-hydroxytryptamine (5-HT), dopamine (DA), gamma-
aminobutyric acid (GABA), and glutamate (Glu), are essential transductors in the Gut-Brain …
aminobutyric acid (GABA), and glutamate (Glu), are essential transductors in the Gut-Brain …
TRPV1 in pain and itch
F Li, F Wang - Ion Channels in Biophysics and Physiology, 2022 - Springer
Transient receptor potential vanilloid type 1 (TRPV1) is a nonselective cation channel that is
intensively expressed in the peripheral nerve system and involved in a variety of …
intensively expressed in the peripheral nerve system and involved in a variety of …
The interaction of TRPV1 and lipids: Insights into lipid metabolism
Transient receptor potential vanilloid 1 (TRPV1), a non-selective ligand-gated cation
channel with high permeability for Ca2+, has received considerable attention as potential …
channel with high permeability for Ca2+, has received considerable attention as potential …
[HTML][HTML] Current state and future perspectives of cytochrome P450 enzymes for C–H and C= C oxygenation
Cytochrome P450 enzymes (CYPs) catalyze a series of C–H and C= C oxygenation
reactions, including hydroxylation, epoxidation, and ketonization. They are attractive …
reactions, including hydroxylation, epoxidation, and ketonization. They are attractive …
Involvement of intestinal enteroendocrine cells in neurological and psychiatric disorders
L Yu, Y Li - Biomedicines, 2022 - mdpi.com
Neurological and psychiatric patients have increased dramatically in number in the past few
decades. However, effective treatments for these diseases and disorders are limited due to …
decades. However, effective treatments for these diseases and disorders are limited due to …
Optogenetic modulation of electroacupuncture analgesia in a mouse inflammatory pain model
Peripheral tissue damage and associated inflammation can trigger neuroplastic changes in
somatic pain pathways, such as reduced neuronal firing thresholds and synaptic …
somatic pain pathways, such as reduced neuronal firing thresholds and synaptic …
[引用][C] Goods and bads of the endocannabinoid system as a therapeutic target: Lessons learned after 30 years
Experience with dronabinol consumption facilitated a stimulant effect of alcohol and affected alcohol-related changes in frontal cortical endocannabinoid levels in …
DT Sangiamo, MJ Weingarten, NG Nelson… - Behavioural Brain …, 2023 - Elsevier
Combined use of cannabis and alcohol is common in adolescents. However, the extent to
which such polydrug exposure affects the brain and behaviors remains under-investigated …
which such polydrug exposure affects the brain and behaviors remains under-investigated …
Targeting CB2 and TRPV1: computational approaches for the identification of dual modulators
Both metabotropic (CBRs) and ionotropic cannabinoid receptors (ICRs) have implications in
a range of neurological disorders. The metabotropic canonical CBRs CB1 and CB2 are …
a range of neurological disorders. The metabotropic canonical CBRs CB1 and CB2 are …