ROS-induced lipid peroxidation modulates cell death outcome: mechanisms behind apoptosis, autophagy, and ferroptosis

B Wang, Y Wang, J Zhang, C Hu, J Jiang, Y Li… - Archives of …, 2023 - Springer
Reactive oxygen species (ROS) mediate lipid peroxidation and produce 4-hydroxynonenal
and other related products, which play an important role in the process of cell death …

Oxidative stress and regeneration

M Jaganjac, L Milkovic, N Zarkovic… - Free Radical Biology and …, 2022 - Elsevier
Regeneration is the process of replacing/restoring a damaged cell/tissue/organ to its full
function and is limited respecting complexity of specific organ structures and the level of …

The lipid peroxidation product 4-hydroxynonenal inhibits NLRP3 inflammasome activation and macrophage pyroptosis

CG Hsu, CL Chávez, C Zhang, M Sowden… - Cell Death & …, 2022 - nature.com
Pyroptosis is a form of cell death triggered by the innate immune system that has been
implicated in the pathogenesis of sepsis and acute lung injury. At the cellular level …

Redox mechanism of reactive oxygen species in exercise

F He, J Li, Z Liu, CC Chuang, W Yang, L Zuo - Frontiers in physiology, 2016 - frontiersin.org
It is well known that regular exercise can benefit health by enhancing antioxidant defenses
in the body. However, unaccustomed and/or exhaustive exercise can generate excessive …

Impact of airborne particulate matter on skin: A systematic review from epidemiology to in vitro studies

IM Dijkhoff, B Drasler, BB Karakocak… - Particle and fibre …, 2020 - Springer
Background Air pollution is killing close to 5 million people a year, and harming billions
more. Air pollution levels remain extremely high in many parts of the world, and air pollution …

Docosahexaenoic acid (DHA): An essential nutrient and a nutraceutical for brain health and diseases

GY Sun, A Simonyi, KL Fritsche, DY Chuang… - … and Essential Fatty …, 2018 - Elsevier
Docosahexaenoic acid (DHA), a polyunsaturated fatty acid (PUFA) enriched in
phospholipids in the brain and retina, is known to play multi-functional roles in brain health …

Interplay between lipid metabolism and autophagy

Y Xie, J Li, R Kang, D Tang - Frontiers in cell and developmental …, 2020 - frontiersin.org
Autophagy is a self-eating process of using lysosomes to degrade macromolecular
substances (eg, proteins and organelles) that are damaged, degenerated, or aging. Lipid …

Free radicals as a double-edged sword: The cancer preventive and therapeutic roles of curcumin

N Gupta, K Verma, S Nalla, A Kulshreshtha, R Lall… - Molecules, 2020 - mdpi.com
Free radicals, generally composed of reactive oxygen species (ROS) and reactive nitrogen
species (RNS), are generated in the body by various endogenous and exogenous systems …

Lipid oxidation and its implications to meat quality and human health

X Huang, DU Ahn - Food science and biotechnology, 2019 - Springer
Lipid oxidation not only negatively influences the sensory characteristics but also the
functional characteristics of meat. During the process, various primary and secondary by …

[HTML][HTML] 4-Hydroxynonenal (HNE) modified proteins in metabolic diseases

JP Castro, T Jung, T Grune, W Siems - Free Radical Biology and Medicine, 2017 - Elsevier
Hydroxynonenal (HNE) is one of the quantitatively most important products of lipid
peroxidation. Due to its high toxicity it is quickly metabolized, however, a small share of HNE …