The respiratory epithelium provides a physical, functional, and immunologic barrier to
protect the host from the potential harming effects of inhaled environmental particles and to …

The house dust mite (HDM) is a major perennial allergen source and a significant cause of
allergic rhinitis and allergic asthma. However, awareness of the condition remains generally …

Environmental variations induced by industrialization and climate change partially explain
the increase in prevalence and severity of allergic disease. One possible mechanism is the …

Over 100 million women use progesterone therapies worldwide. Despite having
immunomodulatory and repair properties, their effects on the outcome of viral diseases …

Background A defective epithelial barrier is found in patients with allergic rhinitis (AR) and
asthma; however, the underlying mechanisms remain poorly understood. Histone …

Chronic inflammatory diseases, including allergies and asthma, are the result of complex
gene-environment interactions. One of the most challenging questions in this regard relates …

A large number of allergens have been discovered but we know little about their potential to
induce inflammation (allergenic activity) and symptoms. Nowadays, the clinical importance …

In spite of substantial advances in defining the immunobiology and function of structural
cells in lung diseases there is still insufficient knowledge to develop fundamentally new …

Precision allergy molecular diagnostic applications (PAMD@) is increasingly entering
routine care. Currently, more than 130 allergenic molecules from more than 50 allergy …

Epigenetic changes including DNA methylation caused by environmental exposures may
contribute to the heterogeneous inflammatory response in asthma. Here we investigate …