Extracellular vesicles as tools and targets in therapy for diseases

MA Kumar, SK Baba, HQ Sadida… - Signal transduction and …, 2024 - nature.com
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …

Sepsis-induced coagulopathy and disseminated intravascular coagulation

T Iba, M Levi, JH Levy - Seminars in thrombosis and …, 2020 - thieme-connect.com
Disseminated intravascular coagulation (DIC) has been recognized as a deadly
complication in sepsis, and its early recognition followed by appropriate management of the …

Biological properties of extracellular vesicles and their physiological functions

M Yáñez-Mó, PRM Siljander, Z Andreu… - Journal of …, 2015 - Taylor & Francis
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

Host-and microbiota-derived extracellular vesicles, immune function, and disease development

L Macia, R Nanan, E Hosseini-Beheshti… - International journal of …, 2019 - mdpi.com
Extracellular vesicles (EVs) are blebs of either plasma membrane or intracellular
membranes carrying a cargo of proteins, nucleic acids, and lipids. EVs are produced by …

Extracellular vesicles in renal disease

D Karpman, A Ståhl, I Arvidsson - Nature Reviews Nephrology, 2017 - nature.com
Extracellular vesicles, such as exosomes and microvesicles, are host cell-derived packages
of information that allow cell–cell communication and enable cells to rid themselves of …

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

KC Vickers, BT Palmisano, BM Shoucri… - Nature cell …, 2011 - nature.com
Circulating microRNAs (miRNA) are relatively stable in plasma and are a new class of
disease biomarkers. Here we present evidence that high-density lipoprotein (HDL) …

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

B György, TG Szabó, M Pásztói, Z Pál, P Misják… - Cellular and molecular …, 2011 - Springer
Release of membrane vesicles, a process conserved in both prokaryotes and eukaryotes,
represents an evolutionary link, and suggests essential functions of a dynamic extracellular …

Disseminated intravascular coagulation: an update on pathogenesis, diagnosis, and therapeutic strategies

C Papageorgiou, G Jourdi, E Adjambri… - Clinical and applied …, 2018 - journals.sagepub.com
Disseminated intravascular coagulation (DIC) is an acquired clinicobiological syndrome
characterized by widespread activation of coagulation leading to fibrin deposition in the …

[HTML][HTML] Extracellular vesicles in physiological and pathological conditions

Y Yuana, A Sturk, R Nieuwland - Blood reviews, 2013 - Elsevier
Body fluids contain surprising numbers of cell-derived vesicles which are now thought to
contribute to both physiology and pathology. Tools to improve the detection of vesicles are …

Microparticles in hemostasis and thrombosis

AP Owens III, N Mackman - Circulation research, 2011 - Am Heart Assoc
Blood contains microparticles (MPs) derived from a variety of cell types, including platelets,
monocytes, and endothelial cells. In addition, tumors release MPs into the circulation. MPs …