Extracellular vesicles as tools and targets in therapy for diseases
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
Sepsis-induced coagulopathy and disseminated intravascular coagulation
Disseminated intravascular coagulation (DIC) has been recognized as a deadly
complication in sepsis, and its early recognition followed by appropriate management of the …
complication in sepsis, and its early recognition followed by appropriate management of the …
Biological properties of extracellular vesicles and their physiological functions
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
Host-and microbiota-derived extracellular vesicles, immune function, and disease development
L Macia, R Nanan, E Hosseini-Beheshti… - International journal of …, 2019 - mdpi.com
Extracellular vesicles (EVs) are blebs of either plasma membrane or intracellular
membranes carrying a cargo of proteins, nucleic acids, and lipids. EVs are produced by …
membranes carrying a cargo of proteins, nucleic acids, and lipids. EVs are produced by …
Extracellular vesicles in renal disease
D Karpman, A Ståhl, I Arvidsson - Nature Reviews Nephrology, 2017 - nature.com
Extracellular vesicles, such as exosomes and microvesicles, are host cell-derived packages
of information that allow cell–cell communication and enable cells to rid themselves of …
of information that allow cell–cell communication and enable cells to rid themselves of …
MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins
Circulating microRNAs (miRNA) are relatively stable in plasma and are a new class of
disease biomarkers. Here we present evidence that high-density lipoprotein (HDL) …
disease biomarkers. Here we present evidence that high-density lipoprotein (HDL) …
Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles
Release of membrane vesicles, a process conserved in both prokaryotes and eukaryotes,
represents an evolutionary link, and suggests essential functions of a dynamic extracellular …
represents an evolutionary link, and suggests essential functions of a dynamic extracellular …
Disseminated intravascular coagulation: an update on pathogenesis, diagnosis, and therapeutic strategies
C Papageorgiou, G Jourdi, E Adjambri… - Clinical and applied …, 2018 - journals.sagepub.com
Disseminated intravascular coagulation (DIC) is an acquired clinicobiological syndrome
characterized by widespread activation of coagulation leading to fibrin deposition in the …
characterized by widespread activation of coagulation leading to fibrin deposition in the …
[HTML][HTML] Extracellular vesicles in physiological and pathological conditions
Y Yuana, A Sturk, R Nieuwland - Blood reviews, 2013 - Elsevier
Body fluids contain surprising numbers of cell-derived vesicles which are now thought to
contribute to both physiology and pathology. Tools to improve the detection of vesicles are …
contribute to both physiology and pathology. Tools to improve the detection of vesicles are …
Microparticles in hemostasis and thrombosis
AP Owens III, N Mackman - Circulation research, 2011 - Am Heart Assoc
Blood contains microparticles (MPs) derived from a variety of cell types, including platelets,
monocytes, and endothelial cells. In addition, tumors release MPs into the circulation. MPs …
monocytes, and endothelial cells. In addition, tumors release MPs into the circulation. MPs …