2, 5-Diketopiperazines (2, 5-DKPs) are cyclodipeptides obtained by the condensation of two
α-amino acids. They not only abound in nature but are often produced as degradation …

Natural products and small molecules inspired by them are enjoying a resurgence of interest
because they intersect biological space effectively and selectively. On account of their …

The importance of palladium‐catalyzed cross coupling reactions in contemporary organic
synthesis is undisputed and underlined by the Nobel Prize for Chemistry in 2010. In addition …

Enantioselective reactions catalyzed by small organic molecules (asymmetric
organocatalysis) have emerged as one of the most elegant cutting-edge strategies of …

The first catalytic enantioselective hydroxylation reaction of both 3-aryl and 3-alkyl-2-
oxindoles using the DBFOX− Zn (II) complex, leading to pharmaceutically important chiral 3 …

The highly enantioselective catalytic hydroxylation of 3-substituted oxindoles was achieved
by using a phase-transfer catalyst with molecular oxygen as an oxidant. The product then …

The recent emergence of biological activities of chiral 3-substituted-3-hydroxy-2-oxindoles
has inspired synthetic chemists to develop new methodologies for their synthesis. Both …

An efficient asymmetric aldol condensation of ketones with isatins has been developed
using an l-proline-derived bifunctional organocatalyst. This strategy allows the …

A simple, straightforward, and highly efficient pseudo-three-component one-pot synthesis of
a series of pharmaceutically interesting functionalized 3, 3-bis (indol-3-yl) indolin-2-ones (3a …

A direct and metal-free access toward fully substituted pyrazoles and its sulphenylation has
been established through an iodine-mediated three-component [3+ 2] annulation of β …