The importance of serial sarcomere addition for muscle function and the impact of aging
During natural aging, skeletal muscle experiences impairments in mechanical performance
due, in part, to changes in muscle architecture and size, notably with a loss of muscle cross …
due, in part, to changes in muscle architecture and size, notably with a loss of muscle cross …
Stimuli for adaptations in muscle length and the length range of active force exertion—a narrative review
Treatment strategies and training regimens, which induce longitudinal muscle growth and
increase the muscles' length range of active force exertion, are important to improve muscle …
increase the muscles' length range of active force exertion, are important to improve muscle …
Leucine attenuates skeletal muscle wasting via inhibition of ubiquitin ligases
The aim of this study was to assess the effect of leucine supplementation on elements of the
ubiquitin–proteasome system (UPS) in rat skeletal muscle during immobilization. This effect …
ubiquitin–proteasome system (UPS) in rat skeletal muscle during immobilization. This effect …
MuRF1 is a muscle fiber-type II associated factor and together with MuRF2 regulates type-II fiber trophicity and maintenance
MuRF1 is a member of the RBCC (RING, B-box, coiled-coil) superfamily that has been
proposed to act as an atrogin during muscle wasting. Here, we show that MuRF1 is …
proposed to act as an atrogin during muscle wasting. Here, we show that MuRF1 is …
miR‐29c improves skeletal muscle mass and function throughout myocyte proliferation and differentiation and by repressing atrophy‐related genes
Abstract Aim To identify microRNAs (miRs) involved in the regulation of skeletal muscle
mass. For that purpose, we have initially utilized an in silico analysis, resulting in the …
mass. For that purpose, we have initially utilized an in silico analysis, resulting in the …
Age-related differences in the loss and recovery of serial sarcomere number following disuse atrophy in rats
Background Older adults exhibit a slower recovery of muscle mass following disuse atrophy
than young adults. At a smaller scale, muscle fibre cross-sectional area (ie, sarcomeres in …
than young adults. At a smaller scale, muscle fibre cross-sectional area (ie, sarcomeres in …
Ultrasonographic measurements of fascicle length overestimate adaptations in serial sarcomere number
Ultrasound‐derived measurements of muscle fascicle length (FL) are often used to infer
increases (chronic stretch or training) or decreases (muscle disuse or aging) in serial …
increases (chronic stretch or training) or decreases (muscle disuse or aging) in serial …
Mechanical loading by fluid shear stress of myotube glycocalyx stimulates growth factor expression and nitric oxide production
P Juffer, AD Bakker, J Klein-Nulend… - Cell biochemistry and …, 2014 - Springer
Skeletal muscle fibers have the ability to increase their size in response to a mechanical
overload. Finite element modeling data suggest that mechanically loaded muscles in vivo …
overload. Finite element modeling data suggest that mechanically loaded muscles in vivo …
Influence of weighted downhill running training on serial sarcomere number and work loop performance in the rat soleus
A Hinks, K Jacob, P Mashouri, KD Medak… - Biology …, 2022 - journals.biologists.com
Increased serial sarcomere number (SSN) has been observed in rats following downhill
running training due to the emphasis on active lengthening contractions; however, little is …
running training due to the emphasis on active lengthening contractions; however, little is …
Expression of genes related to myostatin signaling during rat skeletal muscle longitudinal growth
In this study we investigated the gene expression of proteins related to myostatin (MSTN)
signaling during skeletal muscle longitudinal growth. To promote muscle growth, Wistar …
signaling during skeletal muscle longitudinal growth. To promote muscle growth, Wistar …