Since the definition of the “12 Principles of Green Chemistry” more than 20 years ago,
chemists have become increasingly mindful of the need to conserve natural resources and …

Organic reactions that involve the direct functionalization of non-activated C–H bonds
represent an attractive class of transformations which maximize atom-and step-economy …

The global impact, over the last 25 years, of the principles of green chemistry and
sustainability, and the pivotal role of the E factor concept in driving resource efficiency and …

Palladium-catalyzed aerobic oxidation reactions have been the focus of industrial
application and extensive research efforts for nearly 60 years. A significant transition …

New methods and strategies for the direct functionalization of C–H bonds are beginning to
reshape the field of retrosynthetic analysis, affecting the synthesis of natural products …

In recent years, the application of mechanical energy to chemical systems has repeatedly
proven beneficial to facilitate chemical transformations in various areas in chemistry. Today …

Transition-metal-catalyzed reactions have been studied since the very beginning of the past
century and represent a great success in organic chemistry, along with the birth and growth …

Cu-catalysed arylation reactions devoted to the formation of C–C and C–heteroatom bonds
(Ullmann-type couplings) have acquired great importance in the last decade. This review …

Electrochemical oxidation represents an environmentally friendly solution to conventional
methods that require caustic stoichiometric chemical oxidants. However, C–H …

Continuous-flow liquid phase oxidation chemistry in microreactors receives a lot of attention
as the reactor provides enhanced heat and mass transfer characteristics, safe use of …