Genome and metagenome comparisons based on large amounts of next-generation
sequencing (NGS) data pose significant challenges for alignment-based approaches due to …

Transcription factor binding sites (TFBSs) on the DNA are generally accepted as the key
nodes of gene control. However, the multitudes of TFBSs identified in genome‐wide studies …

Viruses and their host genomes often share similar oligonucleotide frequency (ONF)
patterns, which can be used to predict the host of a given virus by finding the host with the …

Viral sequence classification has wide applications in clinical, epidemiological, structural
and functional categorization studies. Most existing approaches rely on an initial alignment …

Alignment-free genome and metagenome comparisons are increasingly important with the
development of next generation sequencing (NGS) technologies. Recently developed state …

Recent methods for transcriptome-wide N 6-methyladenosine (m6A) profiling have
facilitated investigations into the RNA methylome and established m6A as a dynamic …

We introduce a Bayesian approach to discovering patterns in structurally complex
processes. The proposed method of Bayesian structural inference (BSI) relies on a set of …

There is no single universally accepted definition of 'Complexity'. There are several
perspectives on complexity and what constitutes complex behaviour or complex systems, as …

Shannon entropy has been extensively used for characterizing complexity of time series
arising from chaotic dynamical systems and stochastic processes such as Markov chains …

Generative probabilistic modeling of biological sequences has widespread existing and
potential use across biology and biomedicine, particularly given advances in high …