Drugs with anticholinergic action are widely prescribed in the elderly population due to their
potential clinical benefits. However, these benefits are limited by adverse effects which may …

Purpose Older people are at risk of anticholinergic side effects due to changes affecting drug
elimination and higher sensitivity to drug's side effects. Anticholinergic burden scales (ABS) …

It is generally accepted that chronic opioid use is associated with structural and functional
changes in the human brain that lead to an enhancement of impulsive behavior for …

Background Anticholinergic drugs are commonly prescribed, especially to older adults.
Anticholinergic burden scales (ABS) have been used to evaluate the cumulative effects of …

Anticholinergic cognitive burden (ACB) may be associated with detrimental effects on
mobility and physical independence in older adults. We evaluated the incidence of major …

Pharmacovigilance is defined by the World Health Organization as “the science and
activities relating to the detection, assessment, understanding and prevention of adverse …

Background The rising prevalence of chronic conditions and polypharmacy in the elderly
increases the risk of anticholinergic burden, the cumulative effect of multiple anticholinergic …

Background _ Pharmacovigilance, as defined by the World Health Organization, involves
the scientific and operational activities aimed at identifying, evaluating, comprehending, and …

Executive Summary In the United States, over-the-counter (OTC) products are consumed by
millions of people to self-medicate and, thereby, take an active role in their health care …