CO2 sensing in fungi and beyond

YS Bahn, FA Mühlschlegel - Current opinion in microbiology, 2006 - Elsevier
Carbon dioxide is not only an important gaseous molecule for maintenance of the biosphere
homeostasis, but is also a crucial signalling cue in living cells. Fungal pathogens, including …

[HTML][HTML] Fungal adenylyl cyclase integrates CO2 sensing with cAMP signaling and virulence

T Klengel, WJ Liang, J Chaloupka, C Ruoff… - Current Biology, 2005 - cell.com
The ascomycete Candida albicans is the most common fungal pathogen in
immunocompromised patients [1]. Its ability to change morphology, from yeast to filamentous …

Metabolic flexibility and extensive adaptability governing multiple drug resistance and enhanced virulence in Candida albicans

SA Padder, A Ramzan, I Tahir, R Rehman… - Critical reviews in …, 2022 - Taylor & Francis
Commensal fungus-Candida albicans turn pathogenic during the compromised immunity of
the host, causing infections ranging from superficial mucosal to dreadful systemic ones. C …

Cryptococcus neoformans Senses CO2 through the Carbonic Anhydrase Can2 and the Adenylyl Cyclase Cac1

EG Mogensen, G Janbon, J Chaloupka… - Eukaryotic …, 2006 - Am Soc Microbiol
Cryptococcus neoformans, a fungal pathogen of humans, causes fatal meningitis in
immunocompromised patients. Its virulence is mainly determined by the elaboration of a …

Prevalence, associated factors, and appropriateness of empirical treatment of trichomoniasis, bacterial vaginosis, and vulvovaginal candidiasis among women with …

SH Huang, HC Hsu, TF Lee, HM Fan… - Microbiology …, 2023 - Am Soc Microbiol
ABSTRACT Trichomoniasis (TV), bacterial vaginosis (BV), and vulvovaginal candidiasis
(VVC) are the most common causes of vaginitis. This study investigated the prevalence of …

Development of Itraconazole‐Loaded Polymeric Nanoparticle Dermal Gel for Enhanced Antifungal Efficacy

HN Ho, TG Le, TTT Dao, TH Le, TTH Dinh… - Journal of …, 2020 - Wiley Online Library
Fungal infection of the skin is one of the most common dermatological diseases in the world.
Gel formulations are among the most suitable dosage forms for topical use to treat …

Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal β-carbonic anhydrase from Candida albicans with sulfonamides

A Innocenti, RA Hall, C Schlicker, A Scozzafava… - Bioorganic & medicinal …, 2009 - Elsevier
The β-carbonic anhydrase (CA, EC 4.2. 1.1) from the fungal pathogen Candida albicans
(Nce103) is involved in a CO2 sensing pathway critical for the pathogen life cycle and …

Sensing, physiological effects and molecular response to elevated CO2 levels in eukaryotes

K Sharabi, E Lecuona, IT Helenius… - Journal of cellular …, 2009 - Wiley Online Library
CO2 transport into cells• CO2 sensing in cells and organisms–CO2 sensing in mammalian
neuronal cells–CO2 sensing in peripheral chemoreceptors–CO2 sensing in Central …

Antiseptic efficacy of two mouth rinses in the oral cavity to identify a suitable rinsing solution in radiation-or chemotherapy induced mucositis

P Zwicker, M Freitag, FH Heidel, T Kocher, A Kramer - BMC Oral Health, 2023 - Springer
Objectives Oral mucositis caused by intensive cancer chemotherapy or radiotherapy
frequently results in pronounced damage of the oral mucosa leading to painful oral hygiene …

Molecular networks in the fungal pathogen Candida albicans

RA Hall, F Cottier, FA Mühlschlegel - Advances in applied microbiology, 2009 - Elsevier
Candida albicans is an important opportunistic fungal pathogen of humans. Its success as a
commensal and pathogen extends from its ability to switch between both yeast and hyphal …