Implications of HIV diversity for the HIV-1 pandemic
J Hemelaar - Journal of Infection, 2013 - Elsevier
HIV-1 genetic variability within individuals and populations plays a central role in the HIV
pandemic. Multiple zoonotic transmissions of SIV to humans have resulted in distinct HIV …
pandemic. Multiple zoonotic transmissions of SIV to humans have resulted in distinct HIV …
Impact of clade diversity on HIV-1 virulence, antiretroviral drug sensitivity and drug resistance
S Spira, MA Wainberg, H Loemba… - Journal of …, 2003 - academic.oup.com
HIV-1 infection is characterized by genetic diversity wherein distinct viral subtypes (clades A,
B, C, D, E, F, G, K and O) are expanding in different geographical regions. This article deals …
B, C, D, E, F, G, K and O) are expanding in different geographical regions. This article deals …
Effect of breastfeeding and formula feeding on transmission of HIV-1: a randomized clinical trial
ContextTransmission of human immunodeficiency virus type 1 (HIV-1) is known to occur
through breastfeeding, but the magnitude of risk has not been precisely defined. Whether …
through breastfeeding, but the magnitude of risk has not been precisely defined. Whether …
Rapid detection of HIV-1 proviral DNA for early infant diagnosis using recombinase polymerase amplification
DS Boyle, DA Lehman, L Lillis, D Peterson, M Singhal… - MBio, 2013 - Am Soc Microbiol
Early diagnosis and treatment of human immunodeficiency virus type 1 (HIV-1) infection in
infants can greatly reduce mortality rates. However, current infant HIV-1 diagnostics cannot …
infants can greatly reduce mortality rates. However, current infant HIV-1 diagnostics cannot …
[HTML][HTML] Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo
M Medina-Ramírez, F Garces, A Escolano… - Journal of Experimental …, 2017 - rupress.org
Induction of broadly neutralizing antibodies (bNAbs) by HIV-1 envelope glycoprotein
immunogens would be a major advance toward an effective vaccine. A critical step in this …
immunogens would be a major advance toward an effective vaccine. A critical step in this …
[HTML][HTML] HIV-specific antibodies capable of ADCC are common in breastmilk and are associated with reduced risk of transmission in women with high viral loads
J Mabuka, R Nduati, K Odem-Davis, D Peterson… - PLoS …, 2012 - journals.plos.org
There are limited data describing the functional characteristics of HIV-1 specific antibodies in
breast milk (BM) and their role in breastfeeding transmission. The ability of BM antibodies to …
breast milk (BM) and their role in breastfeeding transmission. The ability of BM antibodies to …
Virologic and immunologic determinants of heterosexual transmission of human immunodeficiency virus type 1 in Africa
ÜS Fideli, SA Allen, R Musonda, S Trask… - AIDS research and …, 2001 - liebertpub.com
More than 80% of the world's HIV-infected adults live in sub-Saharan Africa, where
heterosexual transmission is the predominant mode of spread. The virologic and …
heterosexual transmission is the predominant mode of spread. The virologic and …
Early development of broadly neutralizing antibodies in HIV-1–infected infants
Eliciting protective neutralizing antibodies (NAbs) against HIV-1 is daunting because of the
extensive genetic and antigenic diversity of HIV-1. Moreover, broad and potent responses …
extensive genetic and antigenic diversity of HIV-1. Moreover, broad and potent responses …
Correlates of mother-to-child human immunodeficiency virus type 1 (HIV-1) transmission: association with maternal plasma HIV-1 RNA load, genital HIV-1 DNA …
To determine the effects of plasma, genital, and breast milk human immunodeficiency virus
type 1 (HIV-1) and breast infections on perinatal HIV-1 transmission, a nested case-control …
type 1 (HIV-1) and breast infections on perinatal HIV-1 transmission, a nested case-control …
Unprecedented degree of human immunodeficiency virus type 1 (HIV-1) group M genetic diversity in the Democratic Republic of Congo suggests that the HIV-1 …
N Vidal, M Peeters, C Mulanga-Kabeya… - Journal of …, 2000 - Am Soc Microbiol
The purpose of this study was to document the genetic diversity of human immunodeficiency
virus type 1 (HIV-1) in the Democratic Republic of Congo (DRC; formerly Zaire). A total of …
virus type 1 (HIV-1) in the Democratic Republic of Congo (DRC; formerly Zaire). A total of …