Recent Advances in the Integration of Protein Mechanics and Machine Learning

YL Chen, SW Chang - Extreme Mechanics Letters, 2024 - Elsevier
Mechanics underlies protein properties and behavior. From a theoretical standpoint, it is
possible to derive these based on physical rules. This is appealing because they provide …

HybridGCN for protein solubility prediction with adaptive weighting of multiple features

L Chen, R Wu, F Zhou, H Zhang, JK Liu - Journal of Cheminformatics, 2023 - Springer
The solubility of proteins stands as a pivotal factor in the realm of pharmaceutical research
and production. Addressing the imperative to enhance production efficiency and curtail …

Protsolm: Protein solubility prediction with multi-modal features

Y Tan, J Zheng, L Hong, B Zhou - arXiv preprint arXiv:2406.19744, 2024 - arxiv.org
Understanding protein solubility is essential for their functional applications. Computational
methods for predicting protein solubility are crucial for reducing experimental costs and …

ADH-Enhancer: an attention-based deep hybrid framework for enhancer identification and strength prediction

F Mehmood, S Arshad, M Shoaib - Briefings in Bioinformatics, 2024 - academic.oup.com
Enhancers play an important role in the process of gene expression regulation. In DNA
sequence abundance or absence of enhancers and irregularities in the strength of …

ProSol-multi: Protein solubility prediction via amino acids multi-level correlation and discriminative distribution

H Ghafoor, MN Asim, MA Ibrahim, A Dengel - Heliyon, 2024 - cell.com
Protein solubility prediction is useful for the careful selection of highly effective candidate
proteins for drug development. In recombinant proteins synthesis, solubility prediction is …

Exploring bioinformatics-driven approaches for enhanced diagnosis of Chlamydia trachomatis infections: analysis of target proteins

EK Oladipo, JA Oluwasegun, MH Kibathi… - EMJ …, 2024 - pureportal.strath.ac.uk
Chlamydia trachomatis, a major cause of sexually transmitted infection, poses a range of
symptoms including genital discharge, pain during urination, and abdominal pains in …