Fibronectin type III domain-based fusion proteins
Provided herein are fusion proteins including at least one binding polypeptide and at least
one unstructured polypeptide. The fusion protein may further include at least one linker …
one unstructured polypeptide. The fusion protein may further include at least one linker …
Order and disorder as a design principle for stimuli-responsive biopolymer networks
A Chilkoti, S Roberts - US Patent 11,680,083, 2023 - Google Patents
SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical compound O [C@@ H] 1 [C@@
H](O)[C@ H](O)[C@@ H](CN) O [C@@ H] 1O [C@ H] 1 [C@ H](O)[C@@ H](O [C@@ H] 2 …
H](O)[C@ H](O)[C@@ H](CN) O [C@@ H] 1O [C@ H] 1 [C@ H](O)[C@@ H](O [C@@ H] 2 …
Polymer conjugates having reduced antigenicity and methods of using the same
A Chilkoti, Y Qi, MS Hershfield, NJ Ganson - US Patent 10,364,451, 2019 - Google Patents
Disclosed herein are compositions and methods for reducing the antigenicity of molecules.
The antigenicity of a molecule may be reduced or eliminated by conjugating at least one …
The antigenicity of a molecule may be reduced or eliminated by conjugating at least one …
Compositions and methods for biocontainment of microorganisms
5,362,646 A 5,464,758 A 5,589,362 A 5,650,298 A 5,654,168 A 5,789,156 A 5,814,618 A
5,888,981 A 5,922,927 A 6,004,941 A 6,087,166 A 6,136,954 A 6,242,667 B1 6,252,136 B1 …
5,888,981 A 5,922,927 A 6,004,941 A 6,087,166 A 6,136,954 A 6,242,667 B1 6,252,136 B1 …
Amphiphilic polynucleotides
A Chilkoti, S Zauscher, L Tang… - US Patent 11,965,164, 2024 - Google Patents
Compositions and methods disclosed herein can help provide improved delivery of non-
natural therapeutic nucleotides for the treatment of diseases such as cancer. An example …
natural therapeutic nucleotides for the treatment of diseases such as cancer. An example …
Unstructured non-repetitive polypeptides having lcst behavior
A Chilkoti, T Nicholas, G Kelly - US Patent 12,084,480, 2024 - Google Patents
Described herein are unstructured polypeptides lacking any discernible repeat motif. Also
described herein are fusion proteins including at least one of the unstructured polypeptides …
described herein are fusion proteins including at least one of the unstructured polypeptides …
Dual agonist fusion proteins
A Chilkoti, C Gilroy - US Patent 11,649,275, 2023 - Google Patents
US11649275B2 - Dual agonist fusion proteins - Google Patents US11649275B2 - Dual
agonist fusion proteins - Google Patents Dual agonist fusion proteins Download PDF Info …
agonist fusion proteins - Google Patents Dual agonist fusion proteins Download PDF Info …
Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents
A61K31/704—Compounds having saccharide radicals attached to non-saccharide
compounds by glycosidic linkages attached to a carbocyclic compound, eg phloridzin …
compounds by glycosidic linkages attached to a carbocyclic compound, eg phloridzin …
Engineering organisms resistant to viruses and horizontally transferred genetic elements
Organisms resistant to horizontal gene transfer (HGT), and compositions and methods of
use thereof are provided. The organisms are typically genomically recoded organisms …
use thereof are provided. The organisms are typically genomically recoded organisms …
Surfaces having reduced non-specific binding and antigenicity
A Hucknall, A Chilkoti, D Joh, NJ Ganson, Y Qi… - US Patent …, 2023 - Google Patents
Disclosed herein are compositions and methods for reducing the antigenicity of molecules.
The antigenicity of a molecule may be reduced or eliminated by conjugating at least one …
The antigenicity of a molecule may be reduced or eliminated by conjugating at least one …