Advanced glycation end-products (AGEs): Formation, chemistry, classification, receptors, and diseases related to AGEs
A Twarda-Clapa, A Olczak, AM Białkowska… - Cells, 2022 - mdpi.com
Advanced glycation end-products (AGEs) constitute a non-homogenous, chemically diverse
group of compounds formed either exogeneously or endogeneously on the course of …
group of compounds formed either exogeneously or endogeneously on the course of …
Molecular mechanisms of ROS production and oxidative stress in diabetes
Oxidative stress and chronic inflammation are known to be associated with the development
of metabolic diseases, including diabetes. Oxidative stress, an imbalance between oxidative …
of metabolic diseases, including diabetes. Oxidative stress, an imbalance between oxidative …
RAGE regulation and signaling in inflammation and beyond
K Kierdorf, G Fritz - Journal of leukocyte biology, 2013 - academic.oup.com
ABSTRACT RAGE is a key molecule in the onset and sustainment of the inflammatory
response. New studies indicate that RAGE might represent a new link between the innate …
response. New studies indicate that RAGE might represent a new link between the innate …
Receptor for AGEs (RAGE) as mediator of NF-kB pathway activation in neuroinflammation and oxidative stress
JC Tobon-Velasco, E Cuevas… - CNS & Neurological …, 2014 - ingentaconnect.com
Recently, it has been proposed that the receptor for advanced glycation end-products
(RAGE) plays a crucial role in damaging cellular processes, such as neuroinflammation …
(RAGE) plays a crucial role in damaging cellular processes, such as neuroinflammation …
Advanced glycation end products and their effect on vascular complications in type 2 diabetes mellitus
J Lee, JS Yun, SH Ko - Nutrients, 2022 - mdpi.com
Diabetes is well established as a chronic disease with a high health burden due to mortality
or morbidity from the final outcomes of vascular complications. An increased duration of …
or morbidity from the final outcomes of vascular complications. An increased duration of …
A role for advanced glycation end products in molecular ageing
K Zgutka, M Tkacz, P Tomasiak… - International journal of …, 2023 - mdpi.com
Ageing is a composite process that involves numerous changes at the cellular, tissue, organ
and whole-body levels. These changes result in decreased functioning of the organism and …
and whole-body levels. These changes result in decreased functioning of the organism and …
Receptor for advanced glycation end products acts as a fuel to colorectal cancer development
F Azizian-Farsani, N Abedpoor… - Frontiers in …, 2020 - frontiersin.org
Receptor for advanced glycation end-products (RAGE) is a multiligand binding and single-
pass transmembrane protein taken in diverse chronic inflammatory conditions. RAGE …
pass transmembrane protein taken in diverse chronic inflammatory conditions. RAGE …
Role of RAGE in the Pathogenesis of Neurological Disorders
This review reflects upon our own as well as other investigators' studies on the role of
receptor for advanced glycation end-products (RAGE), bringing up the latest information on …
receptor for advanced glycation end-products (RAGE), bringing up the latest information on …
[HTML][HTML] RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis
M Dahlmann, A Okhrimenko, P Marcinkowski… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Survival of colorectal cancer patients is strongly dependent on development of distant
metastases. S100A4 is a prognostic biomarker and inducer for colorectal cancer metastasis …
metastases. S100A4 is a prognostic biomarker and inducer for colorectal cancer metastasis …
Linking glycation and glycosylation with inflammation and mitochondrial dysfunction in Parkinson's disease
PAQ Videira, M Castro-Caldas - Frontiers in neuroscience, 2018 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disorder, affecting
about 6.3 million people worldwide. PD is characterized by the progressive degeneration of …
about 6.3 million people worldwide. PD is characterized by the progressive degeneration of …