Direct microscopy is widely used for the diagnosis of parasitic infections although it often
requires an experienced microscopist for accurate diagnosis, is labour intensive and not …

Emergence of drugs resistant strains of Plasmodium falciparum has augmented the scourge
of malaria in endemic areas. Antimalaria drugs act on different intracellular targets. The …

We identified 480 persons with positive thick smears for asexual Plasmodium falciparum
parasites, of whom 454 had positive rapid diagnostic tests (RDTs) for the histidine-rich …

Anyone who has cultured Plasmodium falciparum~ s aware that confusion about the identity
of commonly used strains, and inadvertent contamination of one strain with another have …

In the past, assessment of drug efficacy against Plasmodium falciparum malaria has been
performed by microscopy, screening for parasites in blood smears. However, in areas of …

Chloroquine resistance in Plasmodium falciparum is primarily conferred by mutations in
pfcrt. Parasites resistant to chloroquine can display hypersensitivity to other antimalarials; …

The declining efficacy of chloroquine and pyrimethamine/sulphadoxine in the treatment of
human malaria has led to the use of newer antimalarials such as mefloquine and …

Background Trypanosomiasis is a widespread disease of livestock in Nigeria and a major
constraint to the rural economy. The Jos Plateau, Nigeria was free from tsetse flies and the …

The epidemiology of malaria results from the interactions of three gene pools--parasite,
human, and mosquito vector--with one another and with their environment. Methods are …

Resistance of Plasmodium falciparum to many therapeutic agents is an increasing problem
in most endemic areas. The role of the mdr-like gene products of P. falciparum in resistance …