Lung cancer is the primary cause of mortality in the United States and around the globe.
Therapeutic options for lung cancer treatment include surgery, radiation therapy …

The immune-inflammatory response is associated with increased nitro-oxidative stress. The
aim of this mechanistic review is to examine:(a) the role of redox-sensitive transcription …

Allergen immunotherapy is a cornerstone in the treatment of allergic children. The clinical
efficiency relies on a well‐defined immunologic mechanism promoting regulatory T cells and …

Immunotherapy has emerged as an effective strategy for the prevention and treatment of a
variety of diseases, including cancer, infectious diseases, inflammatory diseases, and …

abstract Allergen-specific immunotherapy (AIT) is the mainstay treatment for the cure of
allergic disorders, with depicted efficacy and safety by several trials and meta-analysis. AIT …

Dendritic cells (DCs) are highly specialized professional antigen-presenting cells that
regulate immune responses, maintaining the balance between tolerance and immunity …

Chronic low-grade inflammation has a key role in the aging process, a state called
inflammaging. It is known that the chronic inflammatory condition generates counteracting …

Dendritic cells (DC) are antigen-presenting cells that can communicate with T cells both
directly and indirectly, regulating our adaptive immune responses against environmental …

IL-1 family member IL-37 limits innate inflammation in models of colitis and LPS-induced
shock, but a role in adaptive immunity remains unknown. Here, we studied mice expressing …

T cell activation by dendritic cells (DCs) involves forces exerted by the T cell actin
cytoskeleton, which are opposed by the cortical cytoskeleton of the interacting antigen …