There is an increasing heavy disease burden of major depressive disorder (MDD) globally.
Both high diagnostic heterogeneity and complicated pathological mechanisms of MDD pose …

Healthy reward processing is a complex interplay of several components. Recent self-report
measures of anhedonia, the decrease or loss of hedonic capacity, take this complexity into …

Background Anhedonia is the core symptom of depression. Its presence has been linked to
worsened prognosis. The Dimensional Anhedonia Rating Scale (DARS) is a scale …

Anhedonia is a prevalent symptom across many psychiatric disorders. The contemporary
scope of anhedonia across various models includes interest, reward anticipation, motivation …

Background Although anhedonia is a key symptom of major depressive disorder (MDD),
there is neither a concise nor effective method to distinguish and define anhedonia in MDD …

Adolescent anhedonia is a multidimensional construct defined as the loss of enjoyment or
pleasure across multiple domains of life. Anhedonia is concurrently associated with …

Background Anhedonia, a core diagnostic feature for major depressive disorder (MDD), is
defined as the loss of pleasure and interest in daily activities. Its prevalence in MDD patients …

Objectives Growing evidence suggests that repeated-dose intravenous ketamine in patients
with depression had rapid antianhedonic effects. However, a comparison of the …

To better understand and gauge the severity of anhedonia, the Dimensional Anhedonia
Rating Scale (DARS) was developed which focuses on assessing the four pleasure …

Background Higher levels of stress and negative emotions such as anxiety and depression
have been reported since the beginning of the COVID-19 pandemic, but it remains less clear …