A study on Amygdalin's genotoxicological safety and modulatory activity in human peripheral lymphocytes in vitro

E Erikel, D Yuzbasioglu, F Unal - Environmental and Molecular …, 2023 - Wiley Online Library
Amygdalin (AMY), a plant secondary metabolite containing nitrile, is a major component of
the seeds of Rosaceae family plants. It is known that this compound has many …

Anti-inflammatory and anti-diabetic properties of indanone derivative isolated from Fernandoa adenophylla in vitro and in silico studies

A Rauf, U Rashid, ZA Shah, AA Khalil, M Shah… - Scientific Reports, 2024 - nature.com
Fernandoa adenophylla, due to the presence of phytochemicals, has various beneficial
properties and is used in folk medicine to treat many conditions. This study aimed to isolate …

[PDF][PDF] Investigation of cyto-genotoxic effects of a food sweetener Acesulfame potassium

S Mamur, D Yüzbaşıoğlu, SN Bülbül, F Ünal - Food and Health, 2022 - dergipark.org.tr
Acesulfame potassium (ACE-K) is an artificial sweetener widely used in many foods. This
investigation assessed the cytotoxic effect of ACE-K using MTT assay in human …

Antigenotoxic effect of hyperoside against Mitomycin C and hydrogen peroxide-induced genotoxic damage on human lymphocytes

D Yuzbasioglu, UK Dilek, E Erikel, F Unal - Toxicology in Vitro, 2023 - Elsevier
Hyperoside is a flavonol glycoside isolated from various plant genera such as Hypericum
and Crataegus. It has an important place in the human diet and is used medically to relieve …

High-dose metformin induces a low-glucose dependent genotoxic stress

T Lyu, H Zhou, Y Wang, M Jiang, Q Tao, J Chen… - Food and Chemical …, 2022 - Elsevier
Epidemiological studies have demonstrated that metformin (a cornerstone of diabetes
treatment) has anticancer activity, but the underlying mechanism remains elusive. We aimed …

In vitro genotoxic and antigenotoxic effects of an exopolysaccharide isolated from Lactobacillus salivarius KC27L

BM Yildiz, D Yuzbasioglu, Z Yuksekdag, D Cetin… - Toxicology in Vitro, 2023 - Elsevier
Exopolysaccharide isolated from Lactobacillus salivarius (new genus name
Ligilactobacillus) KC27L strain (EPS KC27L) exhibits antioxidant properties with 1, 1 …

Safety assessment of high fructose corn syrup and fructose used as sweeteners in foods

SN Bulbul, S Mamur, D Yuzbasioglu… - Toxicology mechanisms …, 2024 - Taylor & Francis
Abstract High Fructose Corn Syrup (HFCS) and Fructose (FR) are widely used sweeteners
in many foods and beverages. This study aimed at investigating the cytotoxic effects of …

Genotoxic effects of gadobutrol and gadoversetamide active substances used in magnetic resonance imaging in human peripheral lymphocytes in vitro

E Akbas, F Unal, D Yuzbasioglu - Drug and Chemical Toxicology, 2022 - Taylor & Francis
Gadobutrol and gadoversetamide are gadolinium-based contrast agents (GBCAs) widely
used during magnetic resonance imaging examination. In this study, the genotoxicity of two …

Ecotoxicological assessment of metformin as an antidiabetic water residue treated by electron beam accelerator irradiation

FK Tominaga, JMS de Jesus, N Klanovicz… - Discover Water, 2024 - Springer
Metformin (MET), an antidiabetic compound, has received increasing attention, as it cannot
be effectively removed during conventional wastewater treatment processes and may act as …

Çevresel Kirleticilerin anne Sütünden Izole Edilmiş Epitel Hücrelerindeki dna Hasarına Etkisi

HA Taşyıkan - 2023 - search.proquest.com
Günlük yaşantımızda gıda, tüketim ürünleri ve çevresel hava kirliliği gibi nedenlerle maruz
kaldığımız çevresel kimyasal kirleticiler, tüm dünyada hem insan sağlığı hem de doğa ve …