[HTML][HTML] Social brain, social dysfunction and social withdrawal

S Porcelli, N Van Der Wee, S van der Werff… - Neuroscience & …, 2019 - Elsevier
The human social brain is complex. Current knowledge fails to define the neurobiological
processes underlying social behaviour involving the (patho-) physiological mechanisms that …

Embracing diversity in the 5-HT neuronal system

BW Okaty, KG Commons, SM Dymecki - Nature Reviews Neuroscience, 2019 - nature.com
Neurons that synthesize and release 5-hydroxytryptamine (5-HT; serotonin) express a core
set of genes that establish and maintain this neurotransmitter phenotype and distinguish …

Activity patterns of serotonin neurons underlying cognitive flexibility

S Matias, E Lottem, GP Dugué, ZF Mainen - Elife, 2017 - elifesciences.org
Serotonin is implicated in mood and affective disorders. However, growing evidence
suggests that a core endogenous role is to promote flexible adaptation to changes in the …

An update on the role of serotonin and its interplay with dopamine for reward

AG Fischer, M Ullsperger - Frontiers in human neuroscience, 2017 - frontiersin.org
The specific role of serotonin and its interplay with dopamine (DA) in adaptive, reward
guided behavior as well as drug dependance, still remains elusive. Recently, novel methods …

[HTML][HTML] Dorsal raphe dual serotonin-glutamate neurons drive reward by establishing excitatory synapses on VTA mesoaccumbens dopamine neurons

HL Wang, S Zhang, J Qi, H Wang, R Cachope… - Cell reports, 2019 - cell.com
Dorsal raphe (DR) serotonin neurons provide a major input to the ventral tegmental area
(VTA). Here, we show that DR serotonin transporter (SERT) neurons establish both …

Sensory processing sensitivity and serotonin gene variance: Insights into mechanisms shaping environmental sensitivity

JR Homberg, D Schubert, E Asan, EN Aron - … & Biobehavioral Reviews, 2016 - Elsevier
Current research supports the notion that the apparently innate trait Sensory Processing
Sensitivity (SPS) may act as a modulator of development as function of the environment …

An effect of serotonergic stimulation on learning rates for rewards apparent after long intertrial intervals

K Iigaya, MS Fonseca, M Murakami, ZF Mainen… - Nature …, 2018 - nature.com
Serotonin has widespread, but computationally obscure, modulatory effects on learning and
cognition. Here, we studied the impact of optogenetic stimulation of dorsal raphe serotonin …

Reward contributions to serotonergic functions

Z Liu, R Lin, M Luo - Annual review of neuroscience, 2020 - annualreviews.org
The brain serotonin systems participate in numerous aspects of reward processing, although
it remains elusive how exactly serotonin signals regulate neural computation and reward …

Aversive motivation and cognitive control

DM Yee, X Leng, A Shenhav, TS Braver - Neuroscience & Biobehavioral …, 2022 - Elsevier
Aversive motivation plays a prominent role in driving individuals to exert cognitive control.
However, the complexity of behavioral responses attributed to aversive incentives creates …

Modulatory effects of cannabinoids on brain neurotransmission

K Cohen, A Weizman… - European Journal of …, 2019 - Wiley Online Library
Recreational and chronic cannabis use has been associated with a range of acute and
chronic effects including; anti‐nociceptive actions, anxiety, depression, psychotic symptoms …