Chronic spontaneous urticaria (CSU) is a mast cell–driven skin disease characterized by the
recurrence of transient wheals, angioedema, or both for more than 6 weeks. Autoimmunity is …

Cutaneous lesions in patients with mastocytosis are highly heterogeneous and encompass
localized and disseminated forms. Although a classification and criteria for cutaneous …

This update and revision of the international guideline for urticaria was developed following
the methods recommended by Cochrane and the Grading of Recommendations …

This evidence‐and consensus‐based guideline was developed following the methods
recommended by Cochrane and the Grading of Recommendations Assessment …

Hereditary Angioedema (HAE) is a rare and disabling disease. Early diagnosis and
appropriate therapy are essential. This update and revision of the global guideline for HAE …

These recommendations for the definition, diagnosis and management of chronic inducible
urticaria (CI ndU) extend, revise and update our previous consensus report on physical …

Background Chronic spontaneous urticaria (CSU) can be debilitating, difficult to treat, and
frustrating for patients and physicians. Real‐world evidence for the burden of CSU is limited …

This review presents evidence that the skin mast cell, in particular the MCTC subtype, is the
primary effector cell in urticaria. Mast cells are located in the upper dermis, the ideal situation …

Background Omalizumab, a recombinant anti-IgE antibody, effectively treats chronic
spontaneous urticaria. Evidence is lacking in patients with chronic inducible urticarias …

Background The efficacy of omalizumab (anti-IgE) and increased IgE levels in patients with
chronic spontaneous urticaria (CSU) suggest autoallergic mechanisms. Objective We …