The role of cytokines in head and neck squamous cell carcinoma: A review
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy
worldwide, accounting for approximately 6% of all cancer cases and responsible for an …
worldwide, accounting for approximately 6% of all cancer cases and responsible for an …
Interleukin-8 in the tumor immune niche: lessons from comparative oncology
JH Kim - Tumor Microenvironment: The Role of Interleukins–Part …, 2020 - Springer
Abstract Interleukin (IL)-8 is a chemokine that is essential for inflammation and
angiogenesis. IL-8 expression is elevated in tumor cell lines and tissues, as well as in …
angiogenesis. IL-8 expression is elevated in tumor cell lines and tissues, as well as in …
UDCA inhibits hypoxic hepatocellular carcinoma cell–induced angiogenesis through suppressing HIF-1α/VEGF/IL-8 intercellular signaling
W Lin, S Li, Y Meng, G Huang, S Liang, J Du… - Frontiers in …, 2021 - frontiersin.org
Background: A hypoxic microenvironment may induce angiogenesis and promote the
development of hepatocellular carcinoma (HCC). The aim of this study was to evaluate …
development of hepatocellular carcinoma (HCC). The aim of this study was to evaluate …
MiR-139 targets CXCR4 and inhibits the proliferation and metastasis of laryngeal squamous carcinoma cells
HN Luo, ZH Wang, Y Sheng, Q Zhang, J Yan, J Hou… - Medical Oncology, 2014 - Springer
Our previous studies have showed that chemokine receptor 4 (CXCR4) was over-expressed
in laryngeal squamous cell carcinoma (LSCC). However, the mechanism underlying …
in laryngeal squamous cell carcinoma (LSCC). However, the mechanism underlying …
Circulating interleukin-8 levels explain breast cancer osteolysis in mice and humans
A Kamalakar, MS Bendre, CL Washam, TW Fowler… - Bone, 2014 - Elsevier
Skeletal metastases of breast cancer and subsequent osteolysis connote a dramatic change
in the prognosis for the patient and significantly increase the morbidity associated with …
in the prognosis for the patient and significantly increase the morbidity associated with …
CXCR4 pharmacogical inhibition reduces bone and soft tissue metastatic burden by affecting tumor growth and tumorigenic potential in prostate cancer preclinical …
BACKGROUND The majority of prostate cancer (Pca) patient morbidity can be attributed to
bone metastatic events, which poses a significant clinical obstacle. Therefore, a better …
bone metastatic events, which poses a significant clinical obstacle. Therefore, a better …
Epithelial-mesenchymal transition in cancer: Role of the IL-8/IL-8R axis
Z Zhao, S Wang, Y Lin, Y Miao, Y Zeng… - Oncology …, 2017 - spandidos-publications.com
Epithelial-mesenchymal transition (EMT) is a biological process that is associated with
cancer metastasis and invasion. In cancer, EMT promotes cell motility, invasion and distant …
cancer metastasis and invasion. In cancer, EMT promotes cell motility, invasion and distant …
[HTML][HTML] Dissecting the functions of cancer-associated fibroblasts to therapeutically target head and neck cancer microenvironment
L Prieto-Fernández, I Montoro-Jiménez… - Biomedicine & …, 2023 - Elsevier
Head and neck cancers (HNC) are a diverse group of aggressive malignancies with high
morbidity and mortality, leading to almost half-million deaths annually worldwide. A better …
morbidity and mortality, leading to almost half-million deaths annually worldwide. A better …
[HTML][HTML] Circular RNA ABCB10 contributes to laryngeal squamous cell carcinoma (LSCC) progression by modulating the miR-588/CXCR4 axis
J Zhao, M Wang, LN Song, MJ Zhao - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Laryngeal squamous cell carcinoma (LSCC) is a common head and neck cancer with a high
metastasis and poor prognosis. Circular RNAs (circRNAs) are a type of non-coding RNAs …
metastasis and poor prognosis. Circular RNAs (circRNAs) are a type of non-coding RNAs …
Paracrine interleukin-8 affects mesenchymal stem cells through the Akt pathway and enhances human umbilical vein endothelial cell proliferation and migration
L Wang, Y Li, X Zhang, N Liu, S Shen, S Sun… - Bioscience …, 2021 - portlandpress.com
Abstract Interleukin-8 (IL-8) promotes cell homing and angiogenesis, but its effects on
activating human bone marrow mesenchymal stem cells (BMSCs) and promoting …
activating human bone marrow mesenchymal stem cells (BMSCs) and promoting …