Hepatocellular carcinoma (HCC) is the most common primary liver cancer and has been
acknowledged as a leading cause of death among cirrhosis patients. Difficulties in early …

Liver cancer ranks the sixth in cancer incidence and the second in tumor related mortality
worldwide, with over half of the new cases and deaths occur in China. Because of difficulties …

Liver cancer is the second leading cause of cancer‐related deaths, and hepatocellular
carcinoma (HCC) is the most common type. Therefore, molecular targets are urgently …

Activation of hepatic stellate cells (HSCs) represents the primary driving force to promote the
progression of chronic cholestatic liver diseases. We previously reported that cholangiocyte …

Purpose: The aim of our study is to elucidate whether T cells expressing GPC3-targeted
chimeric antigen receptor (CAR) can efficiently eliminate GPC3-positive HCC cells and their …

Background and Aims Glypican 3 (GPC3) is an oncofetal antigen involved in Wnt-dependent
cell proliferation that is highly expressed in hepatocellular carcinoma (HCC). We …

Glypican-3 (GPC3) is a membrane-associated proteoglycan that is specifically up-regulated
in hepatocellular carcinoma (HCC) although rarely or not expressed in normal liver tissues …

Objectives Hepatocellular carcinoma (HCC) is the second leading cause of cancer mortality
worldwide. Alterations in microtubule-associated proteins (MAPs) have been observed in …

Liver cancer is the second leading cause of cancer-related deaths worldwide, and
hepatocellular carcinoma is the most common type. The pathogenesis of hepatocellular …

Nonalcoholic fatty liver disease (NAFLD) represents a spectrum of diseases ranging from
simple steatosis to more severe forms of liver injury including nonalcoholic steatohepatitis …