Biointerface design for vertical nanoprobes

R Elnathan, MG Barbato, X Guo, A Mariano… - Nature Reviews …, 2022 - nature.com
Biointerfaces mediate safe and efficient cell manipulation, which is essential for biomedical
innovations in advanced therapies and diagnostics. The biointerface established by vertical …

Tutorial: using nanoneedles for intracellular delivery

C Chiappini, Y Chen, S Aslanoglou, A Mariano… - Nature …, 2021 - nature.com
Intracellular delivery of advanced therapeutics, including biologicals and supramolecular
agents, is complex because of the natural biological barriers that have evolved to protect the …

Bioinspired bio-voltage memristors

T Fu, X Liu, H Gao, JE Ward, X Liu, B Yin… - Nature …, 2020 - nature.com
Memristive devices are promising candidates to emulate biological computing. However, the
typical switching voltages (0.2-2 V) in previously described devices are much higher than …

A nanoelectrode array for obtaining intracellular recordings from thousands of connected neurons

J Abbott, T Ye, K Krenek, RS Gertner, S Ban… - Nature biomedical …, 2020 - nature.com
Current electrophysiological or optical techniques cannot reliably perform simultaneous
intracellular recordings from more than a few tens of neurons. Here we report a …

Combining PEDOT: PSS polymer coating with metallic 3D nanowires electrodes to achieve high electrochemical performances for neuronal interfacing applications

I Muguet, A Maziz, F Mathieu, L Mazenq… - Advanced …, 2023 - Wiley Online Library
This study presents a novel approach to improve the performance of microelectrode arrays
(MEAs) used for electrophysiological studies of neuronal networks. The integration of 3D …

Advances in cell-conductive polymer biointerfaces and role of the plasma membrane

A Mariano, C Lubrano, U Bruno, C Ausilio… - Chemical …, 2021 - ACS Publications
The plasma membrane (PM) is often described as a wall, a physical barrier separating the
cell cytoplasm from the extracellular matrix (ECM). Yet, this wall is a highly dynamic structure …

Recent advances in three-dimensional microelectrode array technologies for in vitro and in vivo cardiac and neuronal interfaces

JS Choi, HJ Lee, S Rajaraman, DH Kim - Biosensors and Bioelectronics, 2021 - Elsevier
Three-dimensional microelectrode arrays (3D MEAs) have emerged as promising tools to
detect electrical activities of tissues or organs in vitro and in vivo, but challenges in achieving …

Nanocrown electrodes for parallel and robust intracellular recording of cardiomyocytes

Z Jahed, Y Yang, CT Tsai, EP Foster… - Nature …, 2022 - nature.com
Drug-induced cardiotoxicity arises primarily when a compound alters the
electrophysiological properties of cardiomyocytes. Features of intracellular action potentials …

3D electrodes for bioelectronics

YH Cho, YG Park, S Kim, JU Park - Advanced Materials, 2021 - Wiley Online Library
In recent studies related to bioelectronics, significant efforts have been made to form 3D
electrodes to increase the effective surface area or to optimize the transfer of signals at …

High-throughput DNA synthesis for data storage

M Yu, X Tang, Z Li, W Wang, S Wang, M Li… - Chemical Society …, 2024 - pubs.rsc.org
With the explosion of digital world, the dramatically increasing data volume is expected to
reach 175 ZB (1 ZB= 1012 GB) in 2025. Storing such huge global data would consume tons …