Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI)
Pulmonary hypertension (PH) is highly heterogeneous and despite treatment advances it
remains a life-shortening condition. There have been significant advances in imaging …
remains a life-shortening condition. There have been significant advances in imaging …
Image‐based computational fluid dynamics in the lung: virtual reality or new clinical practice?
KS Burrowes, J De Backer… - … Reviews: Systems Biology …, 2017 - Wiley Online Library
The development and implementation of personalized medicine is paramount to improving
the efficiency and efficacy of patient care. In the respiratory system, function is largely …
the efficiency and efficacy of patient care. In the respiratory system, function is largely …
Evolution of hemodynamic forces in the pulmonary tree with progressively worsening pulmonary arterial hypertension in pediatric patients
W Yang, M Dong, M Rabinovitch, FP Chan… - … and modeling in …, 2019 - Springer
Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling
resulting in right ventricular (RV) dysfunction and ultimately RV failure. Mechanical stimuli …
resulting in right ventricular (RV) dysfunction and ultimately RV failure. Mechanical stimuli …
Patient-specific computational modeling of blood flow in the pulmonary arterial circulation
VO Kheyfets, L Rios, T Smith, T Schroeder… - Computer methods and …, 2015 - Elsevier
Computational fluid dynamics (CFD) modeling of the pulmonary vasculature has the
potential to reveal continuum metrics associated with the hemodynamic stress acting on the …
potential to reveal continuum metrics associated with the hemodynamic stress acting on the …
4D magnetic resonance flow imaging for estimating pulmonary vascular resistance in pulmonary hypertension
VO Kheyfets, M Schafer, CA Podgorski… - Journal of Magnetic …, 2016 - Wiley Online Library
Purpose To develop an estimate of pulmonary vascular resistance (PVR) using blood flow
measurements from 3D velocity‐encoded phase contract magnetic resonance imaging …
measurements from 3D velocity‐encoded phase contract magnetic resonance imaging …
Simulation of unsteady blood flows in a patient‐specific compliant pulmonary artery with a highly parallel monolithically coupled fluid‐structure interaction algorithm
Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient‐
specific arteries for understanding certain cardiovascular diseases. The techniques work …
specific arteries for understanding certain cardiovascular diseases. The techniques work …
3D vortex‐energetics in the left pulmonary artery for differentiating pulmonary arterial hypertension and pulmonary venous hypertension groups using 4D flow MRI
MSM Elbaz, M Shafeghat, BH Freed… - Journal of Magnetic …, 2024 - Wiley Online Library
Background Pulmonary hypertension (PH) is a life‐threatening. Differentiation pulmonary
arterial hypertension (PAH) from pulmonary venous hypertension (PVH) is important due to …
arterial hypertension (PAH) from pulmonary venous hypertension (PVH) is important due to …
Coagulation profiles of pulmonary arterial hypertension patients, assessed by non-conventional hemostatic tests and markers of platelet activation and endothelial …
Many pathophysiologic processes of pulmonary arterial hypertension (PAH), namely, excess
vasoconstriction, vascular remodeling and in situ thrombosis, involve the coagulation …
vasoconstriction, vascular remodeling and in situ thrombosis, involve the coagulation …
Toward vasculature in skeletal muscle-on-a-chip through thermo-responsive sacrificial templates
Developing new approaches for vascularizing synthetic tissue systems will have a
tremendous impact in diverse areas. One area where this is particularly important is …
tremendous impact in diverse areas. One area where this is particularly important is …
Circulating miRNAs in pediatric pulmonary hypertension show promise as biomarkers of vascular function
VO Kheyfets, CC Sucharov, U Truong… - Oxidative medicine …, 2017 - Wiley Online Library
Background/Objectives. The objective of this study was to evaluate the utility of circulating
miRNAs as biomarkers of vascular function in pediatric pulmonary hypertension. Method …
miRNAs as biomarkers of vascular function in pediatric pulmonary hypertension. Method …